PIPERAZINE COMPOUND HAVING A PGDS INHIBITORY EFFECT

Title:

PIPERAZINE COMPOUND HAVING A PGDS INHIBITORY EFFECT

Document Type and Number:

WIPO Patent Application WO/2011/090062

Kind Code:

A1

Abstract:

Disclosed are a piperazine compound represented by formula (1) and a salt thereof. (In the formula, X represents CH or a N atom, R1 represents a C1-6 alkyl group; R2 represents any of a C1-6 alkyl group optionally having a substituted base, a C2-6 alkenyl group optionally having a substituted base, a -(C=O)-N(R3)(R4) group, or a -(C=O)-OR5 group; R3 and R4 can be the same or different and represent a hydrogen atom, or a C1-6 alkyl group optionally having a substituted group; or, R3 and R4, together with the nitrogen atom bound to each, may optionally form a saturated heterocyclic group; and R5 represents a hydrogen atom, or a C1-6 alkyl group or an aralkyl group optionally having a substituted group.)

Inventors:

URADE YOSHIHIRO (JP)
KITADE MAKOTO (JP)
SHIGENO KAZUHIKO (JP)
YAMANE KEIKO (JP)
TANAKA KATSUNAO (JP)

Application Number:

PCT/JP2011/050840

Publication Date:

July 28, 2011

Filing Date:

January 19, 2011

Export Citation:

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Assignee:

TAIHO PHARMACEUTICAL CO LTD (JP)
URADE YOSHIHIRO (JP)
KITADE MAKOTO (JP)
SHIGENO KAZUHIKO (JP)
YAMANE KEIKO (JP)
TANAKA KATSUNAO (JP)

International Classes:

A61K31/496; C07D401/14; A61K31/5377; A61P3/04; A61P7/04; A61P9/10; A61P11/02; A61P11/06; A61P15/08; A61P17/00; A61P17/04; A61P17/10; A61P19/02; A61P21/00; A61P25/04; A61P25/20; A61P27/14; A61P27/16; A61P29/00; A61P37/06; A61P37/08; A61P43/00; C07D401/12; C07D409/12

Domestic Patent References:

WO2008108957A2

2008-09-12

Foreign References:

JP2004511553A	2004-04-15
JP2004520435A	2004-07-08
JP2008546784A	2008-12-25

Other References: