Title:
PIPERIDINE ISOXAZOLE AND ISOTHIAZOLE OREXIN RECEPTOR ANTAGONISTS
Document Type and Number:
WIPO Patent Application WO/2016/065585
Kind Code:
A1
Abstract:
The present invention is directed to piperidine isoxazole and isothiazole orexin compounds which are antagonists of orexin receptors. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the prevention or treatment of such diseases in which orexin receptors are involved.
Inventors:
LIVERTON NIGEL (US)
KUDUK SCOTT D (US)
BESHORE DOUGLAS (US)
LUO YUNFU (CN)
MENG NA (CN)
YU TINGTING (CN)
KUDUK SCOTT D (US)
BESHORE DOUGLAS (US)
LUO YUNFU (CN)
MENG NA (CN)
YU TINGTING (CN)
Application Number:
PCT/CN2014/089933
Publication Date:
May 06, 2016
Filing Date:
October 30, 2014
Export Citation:
Assignee:
MERCK SHARP & DOHME (US)
LIVERTON NIGEL (US)
KUDUK SCOTT D (US)
BESHORE DOUGLAS (US)
LUO YUNFU (CN)
MENG NA (CN)
YU TINGTING (CN)
LIVERTON NIGEL (US)
KUDUK SCOTT D (US)
BESHORE DOUGLAS (US)
LUO YUNFU (CN)
MENG NA (CN)
YU TINGTING (CN)
International Classes:
C07D413/14; A61P25/00; C07D413/04; C07D417/04; C07D417/14
Domestic Patent References:
| WO2010124055A1 | 2010-10-28 | |||
| WO2008147518A1 | 2008-12-04 | |||
| WO2010048010A1 | 2010-04-29 |
Attorney, Agent or Firm:
WU, FENG & ZHANG CO. (Tower BBeijing Aerospace Cpmiec Building,No. 30 Haidian South Roa, Haidian District Beijing 0, CN)
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