Title:
PLASMACYTOID DENDRITIC CELL PROLIFERATION PROMOTER
Document Type and Number:
WIPO Patent Application WO/2017/022560
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a pharmaceutical, food/beverage, and feed having a plasmacytoid dendritic cell proliferation-promoting effect by promoting the proliferation of plasmacytoid dendritic cells, thereby imparting the dual effect of preventing infection and preventing inflammatory disease. The use of lactic acid bacteria belonging to Lactobacillus helveticus or a culture thereof as an active ingredient made it possible to provide a pharmaceutical, food/beverage, and feed for promoting the proliferation of plasmacytoid dendritic cells within the body.
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Inventors:
OGAWA AKIHIRO (JP)
HOSOYA TOMOHIRO (JP)
SAKAI FUMIHIKO (JP)
HOSOYA TOMOHIRO (JP)
SAKAI FUMIHIKO (JP)
Application Number:
PCT/JP2016/071814
Publication Date:
February 09, 2017
Filing Date:
July 26, 2016
Export Citation:
Assignee:
MEGMILK SNOW BRAND CO LTD (JP)
International Classes:
A61K35/747; A23L33/10; A61P29/00; A61P31/12; A61P37/02; A61P37/04
Foreign References:
| JP2007099628A | 2007-04-19 | |||
| JP2011121923A | 2011-06-23 |
Other References:
KATSUAKI SATO: "pDCs to Men'eki Oto", JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 18 August 2015 (2015-08-18)
GOUBIER ANNE ET AL.: "Plasmacytoid dendritic cells mediate oral tolerance", IMMUNITY, vol. 29, no. 3, 2008, pages 464 - 75, XP055361881
DASGUPTA SURYASARATHI ET AL.: "Plasmacytoid dendritic cells mediate anti-inflammatory responses to a gut commensal molecule via both innate and adaptive mechanisms", CELL HOST & MICROBE, vol. 15, no. 4, 2014, pages 413 - 23, XP028847132
KENTA JONAI ET AL.: "Virus Kansen Bogyo o Ninau Plasmacytoid Jujo Saibo o Kasseika suru Nyusankin no Hakken 1", PROCEEDINGS OF THE ANNUAL MEETING OF JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY, 2011, pages 215, XP009177516
GOUBIER ANNE ET AL.: "Plasmacytoid dendritic cells mediate oral tolerance", IMMUNITY, vol. 29, no. 3, 2008, pages 464 - 75, XP055361881
DASGUPTA SURYASARATHI ET AL.: "Plasmacytoid dendritic cells mediate anti-inflammatory responses to a gut commensal molecule via both innate and adaptive mechanisms", CELL HOST & MICROBE, vol. 15, no. 4, 2014, pages 413 - 23, XP028847132
KENTA JONAI ET AL.: "Virus Kansen Bogyo o Ninau Plasmacytoid Jujo Saibo o Kasseika suru Nyusankin no Hakken 1", PROCEEDINGS OF THE ANNUAL MEETING OF JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY, 2011, pages 215, XP009177516
Attorney, Agent or Firm:
MOEGI PATENT OFFICE (JP)
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