Title:
PLATELET FACTOR-4 (PF-4) ANALOGS AND THEIR USE
Document Type and Number:
WIPO Patent Application WO2007053952
Kind Code:
B1
Abstract:
The present invention concerns the discovery, synthesis and use of peptidic analogs derived from platelet factor-4 chemokine (PF-4) and their pharmaceutical compositions. These compounds and their pharmaceutical compositions are useful in treating diseases such as : angiogenic related disorders ; hematopoietic disorders in which the stimulation of proliferation of hematopoietic stem cells/precursors ; the protection of hematopoietic cells from chemotherapy related drugs and/or the inhibition of differentiation of hematopoietic precursors are needed ; coagulatory related disorders requiring the inhibition of heparine or the increase in anti-coagulant activated protein C. ; and inflammation related disorders.
Inventors:
MERZOUK AHMED (CA)
ABRAMOVICH CAROLINA (CA)
SALARI HASSAN (CA)
ABRAMOVICH CAROLINA (CA)
SALARI HASSAN (CA)
Application Number:
PCT/CA2006/001848
Publication Date:
June 28, 2007
Filing Date:
November 10, 2006
Export Citation:
Assignee:
CHEMOKINE THERAPEUTICS CORP (CA)
MERZOUK AHMED (CA)
ABRAMOVICH CAROLINA (CA)
SALARI HASSAN (CA)
MERZOUK AHMED (CA)
ABRAMOVICH CAROLINA (CA)
SALARI HASSAN (CA)
International Classes:
C07K16/24; A61K38/19; A61P7/00; A61P37/02; C07K14/52
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