POLY-ADP RIBOSE POLYMERASE (PARP) INHIBITORS

Title:

POLY-ADP RIBOSE POLYMERASE (PARP) INHIBITORS

Document Type and Number:

WIPO Patent Application WO/2018/125961

Kind Code:

A8

Abstract:

The present invention is related to a pharmaceutical composition comprising a pharmaceutically acceptable carrier or diluent and a compound represented by the following structural formula: The present invention is also related a method of treating a subject with a disease which can be ameliorated by inhibition of poly(ADP-ribose)polymerase (PARP). The definitions of the variables are provided herein.

Inventors:

TAKAHASHI TAISUKE (JP)
KLUGE ARTHUR (US)
LAGU BHARAT (US)
JI NAN (US)

Application Number:

PCT/US2017/068636

Publication Date:

May 23, 2019

Filing Date:

December 28, 2017

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Assignee:

MITOBRIDGE INC (US)

International Classes:

C07D401/14; A61K31/517; A61P35/00; C07D239/74; C07D401/08; C07D403/08; C07D405/10; C07D417/08; C07D487/04

Attorney, Agent or Firm:

DAVIS, Steven, G. et al. (US)

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