POLYACETAL OR POLYKETAL AND ETHER POLYMERS

Title:

POLYACETAL OR POLYKETAL AND ETHER POLYMERS

Document Type and Number:

WIPO Patent Application WO/2011/140644

Kind Code:

A8

Abstract:

The present invention relates to polymers represented by the following formula (I): The invention further provides methods for their preparation and methods for site-specific delivery of nucleic acids by combining them with targeting ligands, endosomolytic ligands and/or PK modulator ligands.

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Inventors:

KIZHAKKEDATHU JAYACHANDRAN (CA)
SHENOI RAJESH (CA)
MANOHARAN MUTHIAH (US)
KALLANTHOTTATHIL RAJEEV (US)
NARAYANANNAIR JAYAPRAKASH K (US)

Application Number:

PCT/CA2011/000552

Publication Date:

December 22, 2011

Filing Date:

May 11, 2011

Export Citation:

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Assignee:

UNIV BRITISH COLUMBIA (CA)
ALNYLAM PHARMACEUTICALS INC (US)
KIZHAKKEDATHU JAYACHANDRAN (CA)
SHENOI RAJESH (CA)
MANOHARAN MUTHIAH (US)
KALLANTHOTTATHIL RAJEEV (US)
NARAYANANNAIR JAYAPRAKASH K (US)

International Classes:

C08G65/28; A61K31/7088; A61K47/34; C12N15/00; C12N15/11; C12N15/87

Attorney, Agent or Firm:

CHATTERJEE, Alakananda et al. (P.O. Box 30 Suite 2300,550 Burrard Stree, Vancouver British Columbia V6C 1B5, CA)

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