Title:
POLYCYCLIC COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS
Document Type and Number:
WIPO Patent Application WO/2011/041461
Kind Code:
A3
Abstract:
Described herein are compounds that are antagonists of lysophosphatidic receptor(s). Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such antagonists, alone and in combination with other compounds, for treating LPA-dependent or LPA-mediated conditions or diseases.
Inventors:
CLARK RYAN (US)
STEARNS BRIAN ANDREW (US)
ZHAO LUCY (US)
SEIDERS THOMAS JON (US)
VOLKOTS DEBORAH (US)
ARRUDA JEANNIE M (US)
ZALATAN DAVID NATHAN (US)
STEARNS BRIAN ANDREW (US)
ZHAO LUCY (US)
SEIDERS THOMAS JON (US)
VOLKOTS DEBORAH (US)
ARRUDA JEANNIE M (US)
ZALATAN DAVID NATHAN (US)
Application Number:
PCT/US2010/050786
Publication Date:
August 25, 2011
Filing Date:
September 29, 2010
Export Citation:
Assignee:
AMIRA PHARMACEUTICALS INC (US)
CLARK RYAN (US)
STEARNS BRIAN ANDREW (US)
ZHAO LUCY (US)
SEIDERS THOMAS JON (US)
VOLKOTS DEBORAH (US)
ARRUDA JEANNIE M (US)
ZALATAN DAVID NATHAN (US)
CLARK RYAN (US)
STEARNS BRIAN ANDREW (US)
ZHAO LUCY (US)
SEIDERS THOMAS JON (US)
VOLKOTS DEBORAH (US)
ARRUDA JEANNIE M (US)
ZALATAN DAVID NATHAN (US)
International Classes:
C07D413/06; A61K31/42; A61K31/4245; A61K31/4427; A61P11/06; A61P35/00; C07D261/14; C07D413/04; C07D413/12
Domestic Patent References:
| WO2005123671A1 | 2005-12-29 |
Foreign References:
| US6762200B2 | 2004-07-13 | |||
| US20050124577A1 | 2005-06-09 |
Other References:
See also references of EP 2483269A4
Attorney, Agent or Firm:
WILSON SONSINI GOODRICH & ROSATI et al. (Palo Alto, CA, US)
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