Title:
POLYCYCLIC COMPOUNDS AND METHODS THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/083343
Kind Code:
A1
Abstract:
Among other things, the present disclosure provides technologies, e.g., compounds, compositions, methods, use for preventing or treating various conditions, disorders or diseases. In some embodiments, a condition, disorder or disease is nonalcoholic steatohepatitis.
Inventors:
LEI XIAOGUANG (CN)
WANG XIAOMING (CN)
LI YULONG (CN)
WANG XIAOMING (CN)
LI YULONG (CN)
Application Number:
PCT/CN2022/131653
Publication Date:
May 19, 2023
Filing Date:
November 14, 2022
Export Citation:
Assignee:
HEPAITECH BEIJING BIOPHARMA TECH CO LTD (CN)
International Classes:
C07D413/14; A61K31/56; A61P43/00; C07J9/00; C07J41/00
Domestic Patent References:
| WO2016086218A1 | 2016-06-02 | |||
| WO2018152171A1 | 2018-08-23 | |||
| WO2016086134A1 | 2016-06-02 | |||
| WO2016173524A1 | 2016-11-03 |
Other References:
HUALING XIAO, PENG LI, XIAOLIN LI, HAIYING HE, JIANHUA WANG, FENGXUN GUO, JILIANG ZHANG, LUXIA WEI, HONGMEI ZHANG, YUEYUAN SHI, LI: "Synthesis and Biological Evaluation of a Series of Bile Acid Derivatives as FXR Agonists for Treatment of NASH", ACS MEDICINAL CHEMISTRY LETTERS, AMERICAN CHEMICAL SOCIETY, US, vol. 8, no. 12, 14 December 2017 (2017-12-14), US , pages 1246 - 1251, XP055479859, ISSN: 1948-5875, DOI: 10.1021/acsmedchemlett.7b00318
Attorney, Agent or Firm:
EASTNATION ATTORNEYS AT LAW (CN)
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