Title:
POLYMER-BOUND ANTIBODY CONCER THERAPEUTIC AGENT
Document Type and Number:
WIPO Patent Application WO2005072479
Kind Code:
A3
Abstract:
Described is a cancer therapeutic agent comprising a polymer to which is linked three or more anti-tumor cell antibodies. Soluble polymers of between 6-8 Kd in size are preferred. The antibodies of the polymer can bind to a tumor cell antigen of a tumor cell and induce apoptosis or cell death of the tumor cell. The polymer may be linked to different antibodies to the same tumor antigen or to different tumor antigens. Methods of treating an individual with cancer using the cancer therapeutic agent are also described.
More Like This:
| WO/1993/007270 | PRODUCTION OF GPA NEUROTROPHIC FACTOR |
| WO/2009/157919 | SOLUBLE ErbB3 DETECTION, REGULATION AND TREATMENT OF CANCER |
| JP2018166510 | ANTI-TRANSGLUTAMINASE 2 ANTIBODIES |
Inventors:
EPSTEIN ALAN L (US)
KHAWLI LESLIE A (US)
KHAWLI LESLIE A (US)
Application Number:
PCT/US2005/003676
Publication Date:
April 13, 2006
Filing Date:
January 27, 2005
Export Citation:
Assignee:
UNIV SOUTHERN CALIFORNIA (US)
EPSTEIN ALAN L (US)
KHAWLI LESLIE A (US)
EPSTEIN ALAN L (US)
KHAWLI LESLIE A (US)
International Classes:
A61K39/395; A61K47/48; C07K16/28; C07K16/30; C07K16/46; (IPC1-7): A61K39/395
Foreign References:
| US20020004587A1 | 2002-01-10 | |||
| US20020006404A1 | 2002-01-17 | |||
| US4434150A | 1984-02-28 | |||
| US4256724A | 1981-03-17 |
Other References:
See also references of EP 1708752A4
Download PDF:
Previous Patent: STRUCTURE AND METHOD FOR CREATING TRADEABLE FINANCIAL UNITS
Next Patent: MOTOR-DRIVEN PUMP FOR POOL OR SPA
Next Patent: MOTOR-DRIVEN PUMP FOR POOL OR SPA