Title:
POLYMER-DRUG CONJUGATES
Document Type and Number:
WIPO Patent Application WO/2023/179521
Kind Code:
A1
Abstract:
A polymeric scaffold useful for conjugating with a targeting moiety can form a targeting moiety-polymer-drug conjugate. A targeting moiety-polymer-drug conjugate is prepared from the polymeric scaffold. Compositions comprise the conjugates. Methods of their preparation and methods of treating various disorders with the conjugates or their compositions.
Inventors:
YIN MAO (US)
YI XIANHUA (CN)
LU YINGDONG (CN)
SHI XIAOHE (CN)
XIN LING (CN)
ZHANG GUANGCHAO (CN)
YU JIANI (CN)
SHEN YU (CN)
YI XIANHUA (CN)
LU YINGDONG (CN)
SHI XIAOHE (CN)
XIN LING (CN)
ZHANG GUANGCHAO (CN)
YU JIANI (CN)
SHEN YU (CN)
Application Number:
PCT/CN2023/082434
Publication Date:
September 28, 2023
Filing Date:
March 20, 2023
Export Citation:
Assignee:
PRIMELINK BIOTHERAPEUTICS SHENZHEN CO LTD (CN)
International Classes:
C08G59/02; A61K47/68; C07D207/02
Domestic Patent References:
| WO2004029018A1 | 2004-04-08 | |||
| WO2017083368A1 | 2017-05-18 | |||
| WO2020256545A1 | 2020-12-24 |
Foreign References:
| CN105813655A | 2016-07-27 | |||
| CN105979970A | 2016-09-28 | |||
| KR20220150175A | 2022-11-10 | |||
| US20150306240A1 | 2015-10-29 | |||
| US20200048682A1 | 2020-02-13 |
Other References:
KWON GEEHWAN, KIM MINSEONG, JUNG WOO HYUK, PARK SUEBIN, TAM THI-THANH HUYNH, OH SEUNG-HWAN, CHOI SOO-HYUNG, AHN DONG JUNE, LEE SAN: "Designing Cooperative Hydrogen Bonding in Polyethers with Carboxylic Acid Pendants", MACROMOLECULES, vol. 54, no. 18, 28 September 2021 (2021-09-28), US , pages 8478 - 8487, XP093094759, ISSN: 0024-9297, DOI: 10.1021/acs.macromol.1c01314
Attorney, Agent or Firm:
JUN HE LAW OFFICES (CN)
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