Title:
A POLYMER MICELLE AS MONOLAYER OR LAYER-LAMINATED SURFACE
Document Type and Number:
WIPO Patent Application WO2001032230
Kind Code:
A3
Abstract:
The present invention is directed to a coated biomedical device said micelle having a hydrophilic outer shell and a hydrophobic inner core, or a hydrophobic outer shell and a hydrophilic inner core said micelle comprised of a block copolymer having a HLB value ranging from about 1 to about 40. The medical device may have one coating thereon or multiple coatings. The present invention is also directed to the use of the micelle as a drug carrier.
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Inventors:
KATAOKA KAZUNORI (JP)
NAGASAKI YUKIO (JP)
EMOTO KAZUNORI (JP)
IIJIMA MICHIHIRO (JP)
NAGASAKI YUKIO (JP)
EMOTO KAZUNORI (JP)
IIJIMA MICHIHIRO (JP)
Application Number:
PCT/IB2000/001724
Publication Date:
December 20, 2001
Filing Date:
November 03, 2000
Export Citation:
Assignee:
KATAOKA KAZUNORI (JP)
NAGASAKI YUKIO (JP)
EMOTO KAZUNORI (JP)
IIJIMA MICHIHIRO (JP)
NAGASAKI YUKIO (JP)
EMOTO KAZUNORI (JP)
IIJIMA MICHIHIRO (JP)
International Classes:
A61K47/30; A61K9/00; A61K9/22; A61K9/52; A61L27/00; A61L27/34; A61L27/54; A61L31/00; A61L31/10; B32B5/18; C08F299/00; C08F299/02; C08F299/04; C08G63/06; C08G63/664; C08J7/12; C09D153/00; C09D179/00; A61F2/16; A61K9/107; A61K9/51; (IPC1-7): A61L31/10
Domestic Patent References:
| WO1999026665A2 | 1999-06-03 | |||
| WO1996038726A1 | 1996-12-05 |
Foreign References:
| US4749585A | 1988-06-07 | |||
| EP0822217A1 | 1998-02-04 | |||
| EP0844269A1 | 1998-05-27 |
Other References:
EMOTO KAZUNORI ET AL: "Coating of surfaces with stabilized reactive micelles from poly(ethylene glycol)-poly(DL-lactic acid) block copolymer", LANGMUIR, ACS, WASHINGTON DC, USA, vol. 15, no. 16, 2 July 1999 (1999-07-02), pages 5212 - 5218, XP002172102
EMOTO KAZUNORI ET AL: "Core-shell structured hydrogel thin layer on surfaces by lamination of a poly(ethylene glycol)-b-poly(D,L-lactide) micelle and polyallylamine", LANGMUIR; ACS, WASHINGTON, DC, USA, vol. 16, no. 13, June 2000 (2000-06-01), pages 5738 - 5742, XP002172103
EMOTO KAZUNORI ET AL: "Core-shell structured hydrogel thin layer on surfaces by lamination of a poly(ethylene glycol)-b-poly(D,L-lactide) micelle and polyallylamine", LANGMUIR; ACS, WASHINGTON, DC, USA, vol. 16, no. 13, June 2000 (2000-06-01), pages 5738 - 5742, XP002172103
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