Title:
POLYMER NANOPARTICLE AND CONTRAST AGENT FOR OPTICAL MOLECULAR IMAGING
Document Type and Number:
WIPO Patent Application WO/2009/107859
Kind Code:
A3
Abstract:
Provided are polymer nanoparticles each having a fluorescent dye dispersed in the matrix of a fluorescent polymer, characterized in that the surface of the nanoparticles is protected by a surfactant and fluorescence is emitted via FRET between the fluorescent polymer and the fluorescent dye, and a contrast agent for optical molecular imaging using the polymer nanoparticles.
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Inventors:
ITO SHINZABURO (JP)
NITAHARA SATOSHI (JP)
AOKI HIROYUKI (JP)
MINAMI MASATO (JP)
TOMIDA YOSHINORI (JP)
YANO TETSUYA (JP)
YOSHIMURA KIMIHIRO (JP)
NITAHARA SATOSHI (JP)
AOKI HIROYUKI (JP)
MINAMI MASATO (JP)
TOMIDA YOSHINORI (JP)
YANO TETSUYA (JP)
YOSHIMURA KIMIHIRO (JP)
Application Number:
PCT/JP2009/054108
Publication Date:
August 05, 2010
Filing Date:
February 26, 2009
Export Citation:
Assignee:
UNIV KYOTO (JP)
CANON KK (JP)
ITO SHINZABURO (JP)
NITAHARA SATOSHI (JP)
AOKI HIROYUKI (JP)
MINAMI MASATO (JP)
TOMIDA YOSHINORI (JP)
YANO TETSUYA (JP)
YOSHIMURA KIMIHIRO (JP)
CANON KK (JP)
ITO SHINZABURO (JP)
NITAHARA SATOSHI (JP)
AOKI HIROYUKI (JP)
MINAMI MASATO (JP)
TOMIDA YOSHINORI (JP)
YANO TETSUYA (JP)
YOSHIMURA KIMIHIRO (JP)
International Classes:
C09B67/00
Foreign References:
US20040142102A1 | 2004-07-22 |
Other References:
GRIGALEVIUS: "excitation energy transfer from semi-conducting polymer nanoparticles to surface-bound fluorescent dyes", MACROMOLECULAR RAPID COMMUNICATIONS, vol. 27, 2006, pages 200 - 202, XP002562261
KIETZKE: "novel approaches to polymer blends based on polymer nanoparticles", NATURE MATERIALS, vol. 2, 2003, pages 408 - 412, XP002562262
LANDFESTER: "semiconducting polymer nanospheres in aqueous dispersion prepared by a miniemulsion process", ADVANCED MATERIALS, vol. 14, no. 9, 2002, XP002562263
KIETZKE: "novel approaches to polymer blends based on polymer nanoparticles", NATURE MATERIALS, vol. 2, 2003, pages 408 - 412, XP002562262
LANDFESTER: "semiconducting polymer nanospheres in aqueous dispersion prepared by a miniemulsion process", ADVANCED MATERIALS, vol. 14, no. 9, 2002, XP002562263
Attorney, Agent or Firm:
OKABE, Masao et al. (Fuji Bldg.2-3, Marunouchi 3-chom, Chiyoda-ku Tokyo 05, JP)
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