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Title:
POLYMER NANOPARTICLE AND CONTRAST AGENT FOR OPTICAL MOLECULAR IMAGING
Document Type and Number:
WIPO Patent Application WO/2009/107859
Kind Code:
A3
Abstract:
Provided are polymer nanoparticles each having a fluorescent dye dispersed in the matrix of a fluorescent polymer, characterized in that the surface of the nanoparticles is protected by a surfactant and fluorescence is emitted via FRET between the fluorescent polymer and the fluorescent dye, and a contrast agent for optical molecular imaging using the polymer nanoparticles.

Inventors:
ITO SHINZABURO (JP)
NITAHARA SATOSHI (JP)
AOKI HIROYUKI (JP)
MINAMI MASATO (JP)
TOMIDA YOSHINORI (JP)
YANO TETSUYA (JP)
YOSHIMURA KIMIHIRO (JP)
Application Number:
PCT/JP2009/054108
Publication Date:
August 05, 2010
Filing Date:
February 26, 2009
Export Citation:
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Assignee:
UNIV KYOTO (JP)
CANON KK (JP)
ITO SHINZABURO (JP)
NITAHARA SATOSHI (JP)
AOKI HIROYUKI (JP)
MINAMI MASATO (JP)
TOMIDA YOSHINORI (JP)
YANO TETSUYA (JP)
YOSHIMURA KIMIHIRO (JP)
International Classes:
C09B67/00
Foreign References:
US20040142102A12004-07-22
Other References:
GRIGALEVIUS: "excitation energy transfer from semi-conducting polymer nanoparticles to surface-bound fluorescent dyes", MACROMOLECULAR RAPID COMMUNICATIONS, vol. 27, 2006, pages 200 - 202, XP002562261
KIETZKE: "novel approaches to polymer blends based on polymer nanoparticles", NATURE MATERIALS, vol. 2, 2003, pages 408 - 412, XP002562262
LANDFESTER: "semiconducting polymer nanospheres in aqueous dispersion prepared by a miniemulsion process", ADVANCED MATERIALS, vol. 14, no. 9, 2002, XP002562263
Attorney, Agent or Firm:
OKABE, Masao et al. (Fuji Bldg.2-3, Marunouchi 3-chom, Chiyoda-ku Tokyo 05, JP)
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