Title:
POLYMORPHS OF ACYL SULFONAMIDES
Document Type and Number:
WIPO Patent Application WO/2010/028968
Kind Code:
A3
Abstract:
The application discloses novel polymorphic crystalline forms of 2-[4-Bromo-3-(3-chloro- 5-cyano-phenoxy)-2-fluoro-phenyl]-N-(2-chloro-4-propionylsulfamoyl-phenyl)-acetamide, sodium salt (Ib) with improved stability and physical properties which facilitate manufacturing, handling and formulating for treatment or prophylaxis of HIV mediated diseases, AIDS or ARC, in monotherapy or in combination therapy.
Inventors:
DAVIDSON JAMES PRENTICE (US)
MARTIN MICHAEL (US)
PANG FEI (US)
WONG MARGARET (US)
MARTIN MICHAEL (US)
PANG FEI (US)
WONG MARGARET (US)
Application Number:
PCT/EP2009/061185
Publication Date:
June 10, 2010
Filing Date:
August 31, 2009
Export Citation:
Assignee:
HOFFMANN LA ROCHE (CH)
DAVIDSON JAMES PRENTICE (US)
MARTIN MICHAEL (US)
PANG FEI (US)
WONG MARGARET (US)
DAVIDSON JAMES PRENTICE (US)
MARTIN MICHAEL (US)
PANG FEI (US)
WONG MARGARET (US)
International Classes:
C07C303/44; C07C311/51
Foreign References:
US20050239881A1 | 2005-10-27 |
Attorney, Agent or Firm:
ZHUANG PLODECK, Jianping (4070 Basel, CH)
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