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Title:
POLYMORPHS OF ACYL SULFONAMIDES
Document Type and Number:
WIPO Patent Application WO/2010/028968
Kind Code:
A3
Abstract:
The application discloses novel polymorphic crystalline forms of 2-[4-Bromo-3-(3-chloro- 5-cyano-phenoxy)-2-fluoro-phenyl]-N-(2-chloro-4-propionylsulfamoyl-phenyl)-acetamide, sodium salt (Ib) with improved stability and physical properties which facilitate manufacturing, handling and formulating for treatment or prophylaxis of HIV mediated diseases, AIDS or ARC, in monotherapy or in combination therapy.

Inventors:
DAVIDSON, James Prentice (1662 Latham Street, Mountain View, California, 94041, US)
MARTIN, Michael (3431 Hillview Avenue, Palo Alto, California, 94304, US)
PANG, Fei (1580 Coronach Avenue, Sunnyvale, California, 94087, US)
WONG, Margaret (2460 Oregon Avenue, Redwood City, California, 94061, US)
Application Number:
EP2009/061185
Publication Date:
June 10, 2010
Filing Date:
August 31, 2009
Export Citation:
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Assignee:
F. HOFFMANN-LA ROCHE AG (Grenzacherstrasse 124, Basel, CH-4070, CH)
DAVIDSON, James Prentice (1662 Latham Street, Mountain View, California, 94041, US)
MARTIN, Michael (3431 Hillview Avenue, Palo Alto, California, 94304, US)
PANG, Fei (1580 Coronach Avenue, Sunnyvale, California, 94087, US)
WONG, Margaret (2460 Oregon Avenue, Redwood City, California, 94061, US)
International Classes:
C07C311/51; C07C303/44
Foreign References:
US20050239881A12005-10-27
Attorney, Agent or Firm:
ZHUANG PLODECK, Jianping (Grenzacherstrasse 124, 4070 Basel, CH)
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