Title:
POLYNUCLEOTIDE DELIVERING COMPLEX FOR TARGET CELL
Document Type and Number:
WIPO Patent Application WO/2012/081799
Kind Code:
A1
Abstract:
The present invention provides a polynucleotide delivery system including a cationic polymer to which a rabies virus glycoprotein (RVG)peptide is bound, wherein the cationic polymer includes a biodegradable bond, and a method of delivering polynucleotides to a target cell by using the delivery system.
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Inventors:
KIM WON JONG (KR)
HWANG DO WON (KR)
LEE DONG SOO (KR)
SON SE JIN (KR)
HWANG DO WON (KR)
LEE DONG SOO (KR)
SON SE JIN (KR)
Application Number:
PCT/KR2011/006299
Publication Date:
June 21, 2012
Filing Date:
August 25, 2011
Export Citation:
Assignee:
POSTECH ACAD IND FOUND (KR)
KIM WON JONG (KR)
HWANG DO WON (KR)
LEE DONG SOO (KR)
SON SE JIN (KR)
KIM WON JONG (KR)
HWANG DO WON (KR)
LEE DONG SOO (KR)
SON SE JIN (KR)
International Classes:
C12N15/11; A61K47/42; A61K48/00; C12N15/87
Foreign References:
| US20100233084A1 | 2010-09-16 | |||
| US20100240597A1 | 2010-09-23 | |||
| US20040002466A1 | 2004-01-01 |
Other References:
ZHU, L. ET AL.: "Site-specific delivery of oligonucleotides to hepatocytes after systemic administration", BIOCONJUG. CHEM., vol. 19, no. 1, January 2008 (2008-01-01), pages 290 - 298, XP055101407, DOI: doi:10.1021/bc070126m
ELIYAHU, H. ET AL.: "Polymers for DNA Delivery", MOLECULES, vol. 10, 31 January 2005 (2005-01-31), pages 34 - 64
ELIYAHU, H. ET AL.: "Polymers for DNA Delivery", MOLECULES, vol. 10, 31 January 2005 (2005-01-31), pages 34 - 64
Attorney, Agent or Firm:
Y.P.LEE, MOCK & PARTNERS (Seocho-dong Seocho-gu, Seoul 137-875, KR)
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Claims: