Title:
POLYNUCLEOTIDE ENCODING A NOVEL HUMAN POTASSIUM CHANNEL BETA-SUBUNIT, K+BETAM3
Document Type and Number:
WIPO Patent Application WO2002068587
Kind Code:
A3
Abstract:
The present invention provides novel polynucleotides encoding K+betaM3 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel K+betaM3 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
Inventors:
FEDER JOHN (US)
LEE LIANA (US)
CHEN JIAN (US)
JACKSON DONALD G (US)
RAMANATHAN CHANDRA (US)
SIEMERS NATHAN (US)
CHANG HAN (US)
RYSECK ROLF-PETER (US)
WATSON ANDREW J (US)
CARROLL PAMELA (US)
LEE LIANA (US)
CHEN JIAN (US)
JACKSON DONALD G (US)
RAMANATHAN CHANDRA (US)
SIEMERS NATHAN (US)
CHANG HAN (US)
RYSECK ROLF-PETER (US)
WATSON ANDREW J (US)
CARROLL PAMELA (US)
Application Number:
PCT/US2002/003986
Publication Date:
March 27, 2003
Filing Date:
February 07, 2002
Export Citation:
Assignee:
BRISTOL MYERS SQUIBB CO (US)
FEDER JOHN (US)
LEE LIANA (US)
CHEN JIAN (US)
JACKSON DONALD G (US)
RAMANATHAN CHANDRA (US)
SIEMERS NATHAN (US)
CHANG HAN (US)
RYSECK ROLF-PETER (US)
WATSON ANDREW J (US)
CARROLL PAMELA (US)
FEDER JOHN (US)
LEE LIANA (US)
CHEN JIAN (US)
JACKSON DONALD G (US)
RAMANATHAN CHANDRA (US)
SIEMERS NATHAN (US)
CHANG HAN (US)
RYSECK ROLF-PETER (US)
WATSON ANDREW J (US)
CARROLL PAMELA (US)
International Classes:
C07K14/705; C12N15/12; (IPC1-7): A61K38/16; C07K14/435; C07K14/705; C07K16/18; C12N5/10; C12N15/12; C12N15/63
Domestic Patent References:
| WO1999043696A1 | 1999-09-02 |
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