Title:
POLYNUCLEOTIDES FOR INHIBITION OF POLYPEPTIDE EXPRESSION AND METHODS OF USE
Document Type and Number:
WIPO Patent Application WO2005047321
Kind Code:
A3
Abstract:
The present invention provides polynucleotides that can inhibit expression of polypeptides such as a UbcH7 polypeptide, an E6-AP polypeptide, a mucin-1 polypeptide, or a mucin-2 polypeptide. The present invention also provides methods of using the polynucleotides.
Inventors:
LOGGIE BRIAN W (US)
NAWAZ ZAFAR (US)
NAWAZ ZAFAR (US)
Application Number:
PCT/US2004/038116
Publication Date:
March 30, 2006
Filing Date:
November 15, 2004
Export Citation:
Assignee:
UNIV CREIGHTON (US)
LOGGIE BRIAN W (US)
NAWAZ ZAFAR (US)
LOGGIE BRIAN W (US)
NAWAZ ZAFAR (US)
International Classes:
C12N9/00; A61K31/138; A61K31/381; A61K31/435; C12N15/113
Domestic Patent References:
| WO2003070917A2 | 2003-08-28 |
Foreign References:
| US5849286A | 1998-12-15 | |||
| US5952481A | 1999-09-14 |
Other References:
DELIC JOZO ET AL: "Ubiquitin pathway involvement in human lymphocyte gamma-irradiation-induced apoptosis", MOLECULAR AND CELLULAR BIOLOGY, vol. 13, no. 8, 1993, pages 4875 - 4883, XP002334277, ISSN: 0270-7306
VERMA SEEMA ET AL: "The ubiquitin-conjugating enzyme UBCH7 acts as a coactivator for steroid hormone receptors", MOLECULAR AND CELLULAR BIOLOGY, vol. 24, no. 19, October 2004 (2004-10-01), pages 8716 - 8726, XP002334278, ISSN: 0270-7306
VERMA SEEMA ET AL: "The ubiquitin-conjugating enzyme UBCH7 acts as a coactivator for steroid hormone receptors", MOLECULAR AND CELLULAR BIOLOGY, vol. 24, no. 19, October 2004 (2004-10-01), pages 8716 - 8726, XP002334278, ISSN: 0270-7306
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