Title:
POLYNUCLEOTIDES AND POLYPEPTIDE SEQUENCES INVOLVED IN THE PROCESS OF BONE REMODELING
Document Type and Number:
WIPO Patent Application WO2006063462
Kind Code:
A9
Abstract:
This invention relates, in part, to unique and newly identified genetic polynucleotides involved in the process of bone remodeling; variants and derivatives of the polynucleotides and corresponding polypeptides; uses of the polynucleotides, polypeptides, variants and derivatives; and methods and compositions for the amelioration of symptoms caused by bone remodeling disorders. Disclosed in particular are, the isolation and identification of polynucleotides, polypeptides, variants and derivatives involved in osteoclast activity, validation of the identified polynucleotides for their potential as therapeutic targets and use of the polynucleotides, polypeptides, variants and derivatives for the amelioration of disease states and research purposes.
Inventors:
SOOKNANAN ROY RABINDRANAUTH (CA)
TREMBLAY GILLES BERNARD (CA)
FILION MARIO (CA)
TREMBLAY GILLES BERNARD (CA)
FILION MARIO (CA)
Application Number:
PCT/CA2005/001917
Publication Date:
September 21, 2006
Filing Date:
December 13, 2005
Export Citation:
Assignee:
ALETHIA BIOTHERAPEUTICS INC (CA)
SOOKNANAN ROY RABINDRANAUTH (CA)
TREMBLAY GILLES BERNARD (CA)
FILION MARIO (CA)
SOOKNANAN ROY RABINDRANAUTH (CA)
TREMBLAY GILLES BERNARD (CA)
FILION MARIO (CA)
International Classes:
C12N15/12; A61K31/7088; C07K16/18; C12Q1/68; C40B40/08; G01N33/50
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