Title:
POLYPEPTIDE DELIVERY COMPOSITION
Document Type and Number:
WIPO Patent Application WO/2020/027585
Kind Code:
A3
Abstract:
The present invention relates to a polypeptide delivery composition, which comprises porous artificial chaperone particles having an average pore diameter of 1-100 nm, so as to make polypeptides become stapled, thereby fixedly changing the random-coiled three-dimensional structure of the polypeptides into a stable alpha-helical structure such that the stability and efficiency of the polypeptides can be remarkably improved.
Inventors:
WON CHEOL HEE (KR)
MIN DAL HEE (KR)
MIN DAL HEE (KR)
Application Number:
PCT/KR2019/009564
Publication Date:
May 07, 2020
Filing Date:
July 31, 2019
Export Citation:
Assignee:
LEMONEX INC (KR)
International Classes:
C07K17/14; A61K38/17; A61K47/52; A61P35/00; C07K14/47; C12N9/96; C12N11/14
Domestic Patent References:
| WO2016130092A1 | 2016-08-18 | |||
| WO2003106589A1 | 2003-12-24 |
Foreign References:
| KR20160011565A | 2016-02-01 | |||
| KR20170013842A | 2017-02-07 |
Other References:
FEI, L. ET AL.: "Effect of nanoparticles on protein folding and fibrillogenesis", INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 10, 2009, pages 646 - 655, XP055705336
Attorney, Agent or Firm:
LEECHAE INTELLECTUAL PROPERTY (KR)
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