Title:
POLYPEPTIDE SET TO BE USED IN LIGHT-DEPENDENT GENE RECOMBINATION
Document Type and Number:
WIPO Patent Application WO/2018/190348
Kind Code:
A1
Abstract:
The present invention pertains to a set of two polypeptides to be used in light-dependent gene recombination wherein an N-terminal fragment and a C-terminal fragment of Cre protein having the amino acid sequence of SEQ ID NO: 1 bind respectively to two proteins for light-dependently forming a dimer.
Inventors:
SATO MORITOSHI (JP)
Application Number:
PCT/JP2018/015136
Publication Date:
October 18, 2018
Filing Date:
April 10, 2018
Export Citation:
Assignee:
UNIV TOKYO (JP)
International Classes:
C12N15/62; A01K67/027; C07K19/00; C12N15/63
Domestic Patent References:
WO2004035628A1 | 2004-04-29 |
Foreign References:
JP2015165776A | 2015-09-24 |
Other References:
KAWANO F. ET AL.: "Aphotoactivatable Cre-loxP recombination system for optogenetic genome engineering", NATURE CHEMICAL BIOLOGY, vol. 12, no. 12, 10 October 2016 (2016-10-10), pages 1059 - 1064, XP055506281, Retrieved from the Internet
JULLIEN N. ET AL.: "Regulation of Cre recombinase by ligand-induced complementation of inactive fragments", NUCLEIC ACIDS RESEARCH, vol. 31, no. 21, 1 November 2003 (2003-11-01), pages e131, XP055559221, Retrieved from the Internet
JULLIEN N. ET AL.: "Regulation of Cre recombinase by ligand-induced complementation of inactive fragments", NUCLEIC ACIDS RESEARCH, vol. 31, no. 21, 1 November 2003 (2003-11-01), pages e131, XP055559221, Retrieved from the Internet
Attorney, Agent or Firm:
INABA, Yoshiyuki et al. (JP)
Download PDF: