Title:
POLYPEPTIDES
Document Type and Number:
WIPO Patent Application WO/2020/127374
Kind Code:
A3
Abstract:
The invention provides bispecific polypeptides comprising a first binding domain, designated B1, which is capable of targeting a dendritic cell, and a second binding domain, designated B2, which is capable of targeting a tumour cell-associated antigen. Also provided are pharmaceutical compositions of such bispecific polypeptides and uses of the same in medicine.
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Inventors:
SÄLL ANNA (SE)
ELLMARK PETER (SE)
DERONIC ADNAN (SE)
CARLSSON FREDRIKA (SE)
HÄGERBRAND KARIN (SE)
VON SCHANTZ LAURA (SE)
ELLMARK PETER (SE)
DERONIC ADNAN (SE)
CARLSSON FREDRIKA (SE)
HÄGERBRAND KARIN (SE)
VON SCHANTZ LAURA (SE)
Application Number:
PCT/EP2019/085786
Publication Date:
October 29, 2020
Filing Date:
December 17, 2019
Export Citation:
Assignee:
ALLIGATOR BIOSCIENCE AB (SE)
International Classes:
C07K16/28; A61K39/00; A61P35/00; C07K16/30; C07K16/32
Domestic Patent References:
| WO2019093342A1 | 2019-05-16 |
Foreign References:
| US20180194862A1 | 2018-07-12 |
Other References:
BUSHRA HUSAIN ET AL: "Expanding the Boundaries of Biotherapeutics with Bispecific Antibodies", BIODRUGS, vol. 32, no. 5, 21 August 2018 (2018-08-21), NZ, pages 441 - 464, XP055678494, ISSN: 1173-8804, DOI: 10.1007/s40259-018-0299-9
ANONYMOUS: "AbbVie R&D Day Forward-Looking Statements and Non-GAAP Financial Information", 1 January 2016 (2016-01-01), XP055678496, Retrieved from the Internet [retrieved on 20200322]
E DAHLEN ET AL: "Therapeutic Advances in Vaccines and Immunotherapy Bispecific antibodies in cancer immunotherapy", THERAPEUTIC ADVANCES IN VACCINES AND IMMUNOTHERAPY, 1 March 2018 (2018-03-01), pages 3 - 17, XP055678495, Retrieved from the Internet [retrieved on 20200322], DOI: 10.1177/2515135518763280Therapeutic
ANONYMOUS: "AbbVie R&D Day Forward-Looking Statements and Non-GAAP Financial Information", 1 January 2016 (2016-01-01), XP055678496, Retrieved from the Internet
E DAHLEN ET AL: "Therapeutic Advances in Vaccines and Immunotherapy Bispecific antibodies in cancer immunotherapy", THERAPEUTIC ADVANCES IN VACCINES AND IMMUNOTHERAPY, 1 March 2018 (2018-03-01), pages 3 - 17, XP055678495, Retrieved from the Internet
Attorney, Agent or Firm:
SMITH, Stephen Edward (GB)
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