Title:
POLYSACCHARIDE DERIVATIVE, POLYSACCHARIDE DERIVATIVE-DRUG CONJUGATE, AND METHOD FOR PRODUCING SAME
Document Type and Number:
WIPO Patent Application WO/2022/034889
Kind Code:
A1
Abstract:
[Problem] To provide a novel polysaccharide derivative which can be used to form a conjugate with a drug and can be used as a medical material, and a polysaccharide derivative-drug conjugate which uses the same. [Solution] A polysaccharide derivative obtained by introducing a group represented by formula (A) to a polysaccharide which is acidic, basic or both, and a polysaccharide derivative-drug conjugate of said polysaccharide derivative and a drug.
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Inventors:
ITO TAICHI (JP)
OHTA SEIICHI (JP)
QI PAN (JP)
CHANDEL ARVIND KUMAR SINGH (JP)
ISAJI MITSUKO (JP)
OHTA SEIICHI (JP)
QI PAN (JP)
CHANDEL ARVIND KUMAR SINGH (JP)
ISAJI MITSUKO (JP)
Application Number:
PCT/JP2021/029573
Publication Date:
February 17, 2022
Filing Date:
August 10, 2021
Export Citation:
Assignee:
UNIV TOKYO (JP)
MOCHIDA PHARM CO LTD (JP)
MOCHIDA PHARM CO LTD (JP)
International Classes:
C08B11/15; A61K9/06; A61K9/48; A61K45/00; A61K47/61; C08B37/02; C08B37/04; C08B37/08
Domestic Patent References:
| WO2019189330A1 | 2019-10-03 |
Foreign References:
| JP2001233786A | 2001-08-28 | |||
| JP2020137010A | 2020-08-31 |
Other References:
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MATERIALS SCIENCE AND ENGINEERING: C, vol. 36, 2014, pages 287 - 293
CARBOHYDRATE POLYMERS, vol. 134, 2015, pages 293 - 299
CARBOHYDRATE POLYMERS, vol. 189, 2018, pages 273 - 279
CARBOHYDRATE POLYMERS, vol. 216, 2019, pages 63 - 71
MATERIALS CHEMISTRY FRONTIERS, vol. 2, no. 10, 2018, pages 1765 - 1778
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LEI ZHOU ET AL.: "Injectable Self-Healing Natural Biopolymer-Based Hydrogel Adhesive with Thermoresponsive Reversible Adhesion for Minimally Invasive Surgery", ADVANCED FUNCTIONAL MATERIALS, vol. 31, no. 14, 2021, pages 2007457
CAS , no. 9012-76-4
LIU CHENGBIN, WU YULIN, WANG XIAOJIAN, HU ZHANG, LUO SHENGLIAN: "Multifunctional PEG-grafted chitosan copolymer possessing amino and carboxyl (or formyl) groups", OPEN CHEMISTRY, vol. 8, no. 3, 1 June 2010 (2010-06-01), pages 576 - 581, XP055900330, DOI: 10.2478/s11532-010-0013-3
BUFFA RADOVAN, ODSTRČILOVÁ LUCIE, ŠEDOVÁ PETRA, BASARABOVÁ IVANA, NOVOTNÝ JAROSLAV, VELEBNÝ VLADIMÍR: "Conjugates of modified hyaluronic acid with amino compounds for biomedical applications", CARBOHYDRATE POLYMERS, vol. 189, 1 June 2018 (2018-06-01), GB , pages 273 - 279, XP055900331, ISSN: 0144-8617, DOI: 10.1016/j.carbpol.2018.02.048
LI NAN-NAN; FU CHAO-PING; ZHANG LI-MING: "Using casein and oxidized hyaluronic acid to form biocompatible composite hydrogels for controlled drug release", MATERIALS SCIENCE AND ENGINEERING C, vol. 36, 27 December 2013 (2013-12-27), CH , pages 287 - 293, XP028669076, ISSN: 0928-4931, DOI: 10.1016/j.msec.2013.12.025
MATERIALS SCIENCE AND ENGINEERING: C, vol. 36, 2014, pages 287 - 293
CARBOHYDRATE POLYMERS, vol. 134, 2015, pages 293 - 299
CARBOHYDRATE POLYMERS, vol. 189, 2018, pages 273 - 279
CARBOHYDRATE POLYMERS, vol. 216, 2019, pages 63 - 71
MATERIALS CHEMISTRY FRONTIERS, vol. 2, no. 10, 2018, pages 1765 - 1778
J. BIOMED. NANOTECHNOL., vol. 13, 2017, pages 1647 - 1659
POLYMER BULLETIN, vol. 31, 1993, pages 145 - 149
CARBOHYDRATE POLYMERS, vol. 92, 2013, pages 2163 - 2170
JOURNAL OF CONTROLLED RELEASE, vol. 236, 2016, pages 79 - 89
AMANO Y., EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 138, 2019, pages 105008
AKIRA TAKAHASHI ET AL., BIOMACROMOLECULES, vol. 10, no. 14, 2013, pages 3581 - 3588
VIANNEY DELPLACE ET AL.: "Nonswelling, Ultralow Content Inverse Electron-Demand Diels-Alder Hyaluronan Hydrogels with Tunable Gelation Time: Synthesis", VITRO EVALUATION, ADVANCED FUNCTIONAL MATERIALS, vol. 30, no. 14, 2020
NIMMO, CHELSEA M. ET AL., BIOMACROMOLECULES, vol. 12, no. 3, 2011, pages 824 - 830
RSC ADV., vol. 8, 2018, pages 11036 - 11042
CHIKAKO YOMOTA ET AL., BULL. NATL. HEALTH SCI., vol. 117, 1999, pages 135 - 139
CHIKAKO YOMOTA ET AL., BULL. NATL. INST. HEALTH SCI., vol. 121, 2003, pages 30 - 33
GREG T. HERMANSON: "Bioconjugate Techniques", 2013
"Carboxylic Acids and Derivatives, Esters", 2007, pages: 258 - 283
LEI ZHOU ET AL.: "Injectable Self-Healing Natural Biopolymer-Based Hydrogel Adhesive with Thermoresponsive Reversible Adhesion for Minimally Invasive Surgery", ADVANCED FUNCTIONAL MATERIALS, vol. 31, no. 14, 2021, pages 2007457
CAS , no. 9012-76-4
Attorney, Agent or Firm:
KOBAYASHI Hiroshi et al. (JP)
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