POLYSACCHARIDE DERIVATIVE HAVING MEMBRANE-PERMEABLE PEPTIDE CHAIN

Title:

POLYSACCHARIDE DERIVATIVE HAVING MEMBRANE-PERMEABLE PEPTIDE CHAIN

Document Type and Number:

WIPO Patent Application WO/2016/136707

Kind Code:

A1

Abstract:

This polysaccharide derivative has a partial structure represented by general formula (1). It is preferable that at least one of the amino acids that constitutes X2 of general formula (1) is a basic amino acid. (In the formula, X1 represents a residue obtained by removing a terminal amino acid group and a terminal carboxyl group from a neutral amino acid or ω-amino alkanoic acid, X2 represents a residue obtained by removing a terminal amino group and a terminal carboxyl-group from a membrane-permeable peptide, X3 represents a hydroxyl group, an amino group, a C1-4 alkoxyl group or a benzyloxy group, a represents 0 or 1, and b represents a number from 0-50.)

Inventors:

SAKUMA SHINJI (JP)
MOHRI KOHTA (JP)
HIWATARI KEN-ICHIRO (JP)
OCHIAI KYOHEI (JP)

Application Number:

PCT/JP2016/055173

Publication Date:

September 01, 2016

Filing Date:

February 23, 2016

Export Citation:

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Assignee:

JOSHO GAKUEN EDUCATIONAL FOUND (JP)
ADEKA CORP (JP)

International Classes:

C08B37/08; A61K47/30; C07K9/00

Domestic Patent References:

WO2012118189A1

2012-09-07

Foreign References:

JPH04134096A	1992-05-07
JPH04300900A	1992-10-23
JP2010515678A	2010-05-13
JP2011229495A	2011-11-17

Other References: