Title:
POLYSACCHARIDE-POLYAMINE COPOLYMER AND USE THEREOF IN REDUCING URIC ACID CONCENTRATION IN PLASMA
Document Type and Number:
WIPO Patent Application WO/2016/150341
Kind Code:
A1
Abstract:
Disclosed is a pharmaceutical composition for treating hyperuricemia (HUA). The pharmaceutical composition comprises a polysaccharide-polyamine copolymer and a pharmaceutically acceptable salt thereof as active ingredients. The polysaccharide-polyamine copolymer is formed by copolymerization of the following two parts: a selectively oxidized polysaccharide with 2,3-dialdehydo, and a polyamine with an amino functional group; the polyamine with an amino functional group and the selectively oxidized polysaccharide with 2,3-dialdehydo can form a net structure by means of covalent crosslinking, resulting in a hydrogel with an amino functional group or a granular polysaccharide-polyamine copolymer, wherein the amino functional group in the hydrogel with an amino functional group or the granular polysaccharide-polyamine copolymer can be protonated so as to form a cationic copolymer of a three-dimensional network structure having a protonated site, and the nitrogen content of the cationic copolymer and the nitrogen content of the polysaccharide-polyamine copolymer are above 12.3 wt%, and both the cationic copolymer and the polysaccharide-polyamine copolymer are water-insoluble.
Inventors:
YANG DAZHI (CN)
Application Number:
PCT/CN2016/076715
Publication Date:
September 29, 2016
Filing Date:
March 18, 2016
Export Citation:
Assignee:
YANG DAZHI (CN)
International Classes:
C08B37/00
Domestic Patent References:
| WO2014084790A1 | 2014-06-05 |
Foreign References:
| CN103030813A | 2013-04-10 | |||
| CN101864078A | 2010-10-20 | |||
| CN103041403A | 2013-04-17 |
Attorney, Agent or Firm:
LIU, SHEN & ASSOCIATES (CN)
北京市柳沈律师事务所 (CN)
北京市柳沈律师事务所 (CN)
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