Title:
POMALIDOMIDE CRYSTALLIZATION TECHNOLOGY
Document Type and Number:
WIPO Patent Application WO/2017/219953
Kind Code:
A1
Abstract:
A pomalidomide crystallization technology. The crystallization technology comprises: mixing pomalidomide with mixed solvent A for dissolution, and concentrating an obtained clear solution to obtain pomalidomide crystals. The used crystallization technology has a simple operation, low costs, is safe, efficient, and environmentally friendly, and facilitates industrial production. In addition, the prepared products have a single crystal form and high yield, are stable, and meet the ICH residue limit requirement.
Inventors:
CHEN DAOXIN (CN)
CHEN WEIRONG (CN)
ZHOU GANG (CN)
CHEN WEIRONG (CN)
ZHOU GANG (CN)
Application Number:
PCT/CN2017/089116
Publication Date:
December 28, 2017
Filing Date:
June 20, 2017
Export Citation:
Assignee:
ZHEJIANG HISUN PHARM CO LTD (CN)
International Classes:
C07D401/04; A61P35/00; A61P37/02
Domestic Patent References:
WO2015075694A1 | 2015-05-28 |
Foreign References:
CN104557857A | 2015-04-29 | |||
CN105924426A | 2016-09-07 |
Attorney, Agent or Firm:
UNITALEN ATTORNEYS AT LAW (CN)
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