Title:
POST NERVE INJURY REHABILITATION EFFECT-ENHANCING AGENT COMPRISING ALKYL ETHER DERIVATIVE OR SALT THEREOF
Document Type and Number:
WIPO Patent Application WO/2015/115582
Kind Code:
A1
Abstract:
Provided is a medicinal composition characterized by comprising an alkyl ether derivative represented by general formula [1] [wherein: R1 and R2 are the same or different and represent a hydrogen atom, a halogen atom, an optionally substituted C1-6 alkyl group, an optionally substituted aryl group, etc.; R3 represents an optionally protected hydroxyl group, etc.; and m and n are the same or different and represent an integer of 1 to 6] or a salt thereof. The medicinal composition according to the present invention is useful as a post nerve injury rehabilitation effect-enhancing agent.
Inventors:
TAKAHASHI TAKUYA (JP)
OKUDA TOMOHIRO (JP)
OKUDA TOMOHIRO (JP)
Application Number:
PCT/JP2015/052617
Publication Date:
August 06, 2015
Filing Date:
January 30, 2015
Export Citation:
Assignee:
TOYAMA CHEMICAL CO LTD (JP)
International Classes:
A61K31/397; A61P25/28
Domestic Patent References:
| WO2003045137A1 | 2003-06-05 | |||
| WO2003035647A1 | 2003-05-01 | |||
| WO2007125913A1 | 2007-11-08 |
Foreign References:
| JP2013177410A | 2013-09-09 |
Other References:
TETSUO FUKUSHIMA ET AL.: "T-817MA, a novel neurotrophic agent, improves sodium nitroprusside-induced mitochondrial dysfunction in cortical neurons", NEUROCHEM INT., vol. 48, no. 2, 2006, pages 124 - 30, XP027957878
PLOS ONE, vol. 8, no. 12, 2013, pages E83468
JOURNAL OF NEUROENGINEERING AND REHABILITATION, vol. 10, 2013, pages 112 - 123
W. GREENE ET AL.: "Protective Groups in Organic Synthesis", 2007, JOHN WILEY & SONS, INC, pages: 696 - 868
W. GREENE ET AL.: "Protective Groups in Organic Synthesis", JOHN WILEY & SONS, INC., pages: 16 - 299
W. GREENE ET AL.: "Protective Groups in Organic Synthesis", 2007, JOHN WILEY & SONS, INC., pages: 533 - 643
JOURNAL OF NEUROSCIENCE METHODS, vol. 193, no. 1, 2010, pages 82 - 85
NATURE, vol. 462, no. 7275, 2009, pages 915 - 919
PLOS ONE, vol. 8, 2013, pages E67691
BEHAV BRAIN RES., vol. 20, no. 225, 2011, pages 126 - 34
PLOS ONE, vol. 8, no. 12, 2013, pages E83468
JOURNAL OF NEUROENGINEERING AND REHABILITATION, vol. 10, 2013, pages 112 - 123
W. GREENE ET AL.: "Protective Groups in Organic Synthesis", 2007, JOHN WILEY & SONS, INC, pages: 696 - 868
W. GREENE ET AL.: "Protective Groups in Organic Synthesis", JOHN WILEY & SONS, INC., pages: 16 - 299
W. GREENE ET AL.: "Protective Groups in Organic Synthesis", 2007, JOHN WILEY & SONS, INC., pages: 533 - 643
JOURNAL OF NEUROSCIENCE METHODS, vol. 193, no. 1, 2010, pages 82 - 85
NATURE, vol. 462, no. 7275, 2009, pages 915 - 919
PLOS ONE, vol. 8, 2013, pages E67691
BEHAV BRAIN RES., vol. 20, no. 225, 2011, pages 126 - 34
Download PDF: