Title:
POST-TRANSCRIPTIONALLY CHEMICALLY MODIFIED DOUBLE STRAND RNAS
Document Type and Number:
WIPO Patent Application WO/2018/085752
Kind Code:
A3
Abstract:
Described are post transcriptionally chemically modified double strand RNAs (MdsRNAs) having more than 30 base pairs. The MdsRNAs inhibit gene expression in target organisms. Also described are methods of making and using MdsRNAs.
Inventors:
ARHANCET JUAN (US)
CHEERLA SREEVISHNU (US)
ARHANCET GRACIELA (US)
ROZEMA DAVID (US)
CHEERLA SREEVISHNU (US)
ARHANCET GRACIELA (US)
ROZEMA DAVID (US)
Application Number:
PCT/US2017/060110
Publication Date:
June 07, 2018
Filing Date:
November 06, 2017
Export Citation:
Assignee:
NANOSUR LLC (US)
International Classes:
C07F9/02; C07H21/00; C07H21/02; C12P19/34
Domestic Patent References:
| WO2016028649A1 | 2016-02-25 | |||
| WO2017070151A1 | 2017-04-27 |
Foreign References:
| US20160068837A1 | 2016-03-10 | |||
| US20040142896A1 | 2004-07-22 | |||
| US9102938B2 | 2015-08-11 | |||
| US20150037805A1 | 2015-02-05 | |||
| US20100035761A1 | 2010-02-11 |
Other References:
WATANABE ET AL.: "Reaction of tRNAPhe from Yeast with 1-Fluoro-2,4-dinitrobenzene", EUR. J. BIOCHEM., vol. 89, 1978, pages 425 - 432, XP055490368
Attorney, Agent or Firm:
EKENA, Kirk (US)
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