Title:
PRECURSOR COMPOUND CONNECTED TO SOLID SUPPORT FOR MANUFACTURING 18F RADIOPHARMACEUTICAL, METHOD FOR MANUFACTURING SAME, AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2012/081880
Kind Code:
A2
Abstract:
The present invention relates to a solid precursor in the form of an organic salt, the solid precursor having a solid support, a method for manufacturing same, and an application thereof. The solid precursor of the present invention enables omission of the [18F]fluoride refining process using additional cartridge, and the use of excessive phase-transfer catalyst, and can easily remove remaining substance after reaction through the solid support inside the precursor. The solid precursor of the present invention is very appropriate for an automated synthesis device as an all-in-one system that can carry out overall process of [18F]fluorosis reaction, when used by charging in a cartridge.
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Inventors:
CHI, Dae-Yoon (215-804, Hangaram Apt. 407 Ichon-dong Yongsan-gu, Seoul 140-030, 140-030, KR)
지대윤 (서울 용산구 이촌동 407 한가람아파트 215-804, 140-030 Seoul, 140-030, KR)
LEE, Byoung-Se (C-409, Sanho Apt. Wonhyoro 4-ga Yongsan-gu, Seoul 140-767, 140-767, KR)
이병세 (서울 용산구 원효로4가 산호아파트 C동 409호, 140-767 Seoul, 140-767, KR)
LEE, Jae-Hak (1 Sangwooboram Apt. 497-1 Bugae-dong, Bupyeong-gu, Incheon 403-726, 403-726, KR)
이재학 (인천 부평구 부개동 497-1 상우보람아파트, 403-726 Incheon, 403-726, KR)
지대윤 (서울 용산구 이촌동 407 한가람아파트 215-804, 140-030 Seoul, 140-030, KR)
LEE, Byoung-Se (C-409, Sanho Apt. Wonhyoro 4-ga Yongsan-gu, Seoul 140-767, 140-767, KR)
이병세 (서울 용산구 원효로4가 산호아파트 C동 409호, 140-767 Seoul, 140-767, KR)
LEE, Jae-Hak (1 Sangwooboram Apt. 497-1 Bugae-dong, Bupyeong-gu, Incheon 403-726, 403-726, KR)
이재학 (인천 부평구 부개동 497-1 상우보람아파트, 403-726 Incheon, 403-726, KR)
Application Number:
KR2011/009571
Publication Date:
June 21, 2012
Filing Date:
December 13, 2011
Export Citation:
Assignee:
INDUSTRY-UNIVERSITY COOPERATION FOUNDATION SOGANG UNIVERSITY (Sogang University 1 Sinsu-dong, Mapo-gu, Seoul 121-742, 121-742, KR)
서강대학교산학협력단 (서울 마포구 신수동 1 서강대학교, 121-742 Seoul, 121-742, KR)
CHI, Dae-Yoon (215-804, Hangaram Apt. 407 Ichon-dong Yongsan-gu, Seoul 140-030, 140-030, KR)
지대윤 (서울 용산구 이촌동 407 한가람아파트 215-804, 140-030 Seoul, 140-030, KR)
LEE, Byoung-Se (C-409, Sanho Apt. Wonhyoro 4-ga Yongsan-gu, Seoul 140-767, 140-767, KR)
이병세 (서울 용산구 원효로4가 산호아파트 C동 409호, 140-767 Seoul, 140-767, KR)
LEE, Jae-Hak (1 Sangwooboram Apt. 497-1 Bugae-dong, Bupyeong-gu, Incheon 403-726, 403-726, KR)
서강대학교산학협력단 (서울 마포구 신수동 1 서강대학교, 121-742 Seoul, 121-742, KR)
CHI, Dae-Yoon (215-804, Hangaram Apt. 407 Ichon-dong Yongsan-gu, Seoul 140-030, 140-030, KR)
지대윤 (서울 용산구 이촌동 407 한가람아파트 215-804, 140-030 Seoul, 140-030, KR)
LEE, Byoung-Se (C-409, Sanho Apt. Wonhyoro 4-ga Yongsan-gu, Seoul 140-767, 140-767, KR)
이병세 (서울 용산구 원효로4가 산호아파트 C동 409호, 140-767 Seoul, 140-767, KR)
LEE, Jae-Hak (1 Sangwooboram Apt. 497-1 Bugae-dong, Bupyeong-gu, Incheon 403-726, 403-726, KR)
International Classes:
C08F28/02; A61K51/00; C08F2/38; C08F8/34
Attorney, Agent or Firm:
DAWOOL PATENT AND LAW FIRM (5th Floor, Hyejeon Bldg.224 Bongeunsa-ro, Gangnam-gu, Seoul 135-913, 135-913, KR)
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Claims: