Title:
PREDICTIVE MARKER FOR CANCER TREATMENT
Document Type and Number:
WIPO Patent Application WO/2014/068133
Kind Code:
A8
Abstract:
The present invention provides NOTCH1 gene mutation as a biomarker that is predictive for the response and outcome after treatment with an anti-CD20 antibody in cancer patients.
Inventors:
HALLEK MICHAEL (DE)
STILGENBAUER STEPHAN (DE)
DÖHNER HARTMUT (DE)
KLEIN CHRISTIAN (DE)
UMAÑA PABLO (DE)
STILGENBAUER STEPHAN (DE)
DÖHNER HARTMUT (DE)
KLEIN CHRISTIAN (DE)
UMAÑA PABLO (DE)
Application Number:
PCT/EP2013/073015
Publication Date:
January 08, 2015
Filing Date:
November 05, 2013
Export Citation:
Assignee:
HOFFMANN LA ROCHE (US)
HOFFMANN LA ROCHE (US)
UNIVERSITAETSKLINIKUM ULM (DE)
UNIV KOELN (DE)
HOFFMANN LA ROCHE (US)
UNIVERSITAETSKLINIKUM ULM (DE)
UNIV KOELN (DE)
International Classes:
C12Q1/68
Attorney, Agent or Firm:
KLEIN, Thomas (Grenzacherstrasse 124, Basel, CH)
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