PREGNANE DERIVATIVES AND PROCESS FOR THEIR PREPARATION

Title:

PREGNANE DERIVATIVES AND PROCESS FOR THEIR PREPARATION

Document Type and Number:

WIPO Patent Application WO/1988/007545

Kind Code:

A1

Abstract:

Pregnane derivatives represented by general formula (I) (wherein A1 represents a hydrogen atom or a hydroxy group, A2 represents a substituent such as a hydroxy group when A1 represents a hydrogen atom, or A2 represents a hydrogen atom when A1 represents a hydroxy group, or A1 and A2 are combined together to form an oxo group; D1 represents a substituent such as a hydroxy group, and D2 represents a hydrogen atom, or D1 and D2 are combined together to form an epoxy group or a single bond; D3, D5 and D7 each represents a hydrogen atom, D4 represents a hydroxy group, and D6 represents a substituent such as a hydroxy group, or D3 and D4 may be combined together to form an epoxy group or a single bond, or D4 and D5 may be combined together to form a single bond, D5 and D6 may be combined together to form an epoxy group or a single bond, or D6 and D7 may be combined together to form a single bond; and X1 and X2 each represents a lower alkoxy group or, when combined together, they represent a lower alkylenedioxy or oxo group) and a process for their preparation. The pregnane derivatives are useful as intermediates for synthesizing vitamin D3 having a hydroxy group in the 1alpha-position.

Inventors:

TSUJI JIRO (JP)
TAKAHASHI TAKASHI (JP)
TSUJI MASAO (JP)
NAKAGAWA NAOSHI (JP)
TAKIGAWA TETSUO (JP)

Application Number:

PCT/JP1988/000313

Publication Date:

October 06, 1988

Filing Date:

March 29, 1988

Export Citation:

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Assignee:

KURARAY CO (JP)

International Classes:

C07J9/00; C07J17/00; C07J41/00; C07J51/00; C07J71/00; (IPC1-7): C07J9/00; C07J17/00; C07J41/00; C07J51/00; C07J71/00; C12P33/00

Foreign References:

JPH05350152A

Other References: