Title:
PREPARATION OF AMINE UREA SENSITIVE AMINE OXIDASE INHIBITOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/063696
Kind Code:
A1
Abstract:
Provided are a preparation of amine urea sensitive amine oxidase inhibitor and the use thereof. In particular, dislosed are a compound as shown in formula I, or a stereoisomer or racemate or pharmaceutically acceptable salt thereof. Also disclosed is that the above-mentioned compound can inhibit amine urea sensitive amine oxidase.
Inventors:
LIU SHENGYANG (CN)
DENG JIANWEN (CN)
FENG ZHIYONG (CN)
JIANG LEI (CN)
QIAO ZHI (CN)
SHANG KE (CN)
XIE XIAOPING (CN)
XU XUELI (CN)
XU YUAN (CN)
ZHAO HAIXIA (CN)
DENG JIANWEN (CN)
FENG ZHIYONG (CN)
JIANG LEI (CN)
QIAO ZHI (CN)
SHANG KE (CN)
XIE XIAOPING (CN)
XU XUELI (CN)
XU YUAN (CN)
ZHAO HAIXIA (CN)
Application Number:
PCT/CN2019/107972
Publication Date:
April 02, 2020
Filing Date:
September 25, 2019
Export Citation:
Assignee:
SHANGHAI ENNOVABIO PHARMACEUTICALS CO LTD (CN)
International Classes:
C07D405/14; A61K31/506; A61P3/10; A61P25/00; A61P27/02; A61P29/00; A61P35/00; C07D451/06; C07D471/08; C07D487/08; C07D491/107
Domestic Patent References:
| WO2018151985A1 | 2018-08-23 | |||
| WO2018151985A1 | 2018-08-23 | |||
| WO2018028517A1 | 2018-02-15 | |||
| WO2018028517A1 | 2018-02-15 |
Foreign References:
| CN109251166A | 2019-01-22 | |||
| CN107266332A | 2017-10-20 | |||
| CN101917845A | 2010-12-15 |
Other References:
CHIRAL SEPARATIONS, METHODS AND PROTOCOLS, METHODS IN MOLECULAR BIOLOGY, vol. 243, 2004
A.M. STALCUP, CHIRAL SEPARATIONS, ANNU. REV. ANAL. CHEM., vol. 3, 2010, pages 341 - 63
"VOGEL'S ENCYCLOPEDIA OF PRACTICAL ORGANIC CHEMISTRY", 1991, LONGMAN SCIENTIFIC AND TECHNICAL LTD., pages: 809 - 816
HELLER, ACC. CHEM. RES., vol. 23, 1990, pages 128
GREENE, T. W.P. G. M. WUTS: "Protective Groups in Organic Synthesis", 1999, WILEY
See also references of EP 3858827A4
A.M. STALCUP, CHIRAL SEPARATIONS, ANNU. REV. ANAL. CHEM., vol. 3, 2010, pages 341 - 63
"VOGEL'S ENCYCLOPEDIA OF PRACTICAL ORGANIC CHEMISTRY", 1991, LONGMAN SCIENTIFIC AND TECHNICAL LTD., pages: 809 - 816
HELLER, ACC. CHEM. RES., vol. 23, 1990, pages 128
GREENE, T. W.P. G. M. WUTS: "Protective Groups in Organic Synthesis", 1999, WILEY
See also references of EP 3858827A4
Attorney, Agent or Firm:
XU & PARTNERS, LLC. (CN)
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