Title:
PREPARATION AND APPLICATION OF POLYKETONE COMPOUND HAVING ANTI-NOVEL CORONAVIRUS ACTIVITY
Document Type and Number:
WIPO Patent Application WO/2022/246810
Kind Code:
A1
Abstract:
A preparation method for a polyketone compound having anti-novel coronavirus activity, and an application of a polyketone compound. Solid fermentation is performed on alternaria endophytic fungi Alternaria sp., and a polyketone monomeric compound is obtained from a fermented product by using a series of separation and purification methods. The compound has the structure as represented by formula (I), and has anti-novel coronavirus activity.
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Inventors:
LU XUAN (CN)
TANG XIAOYUAN (CN)
QI JUNKAI (CN)
FENG BAOMIN (CN)
TANG CHUAN (CN)
FENG WEIXING (CN)
TANG XIAOYUAN (CN)
QI JUNKAI (CN)
FENG BAOMIN (CN)
TANG CHUAN (CN)
FENG WEIXING (CN)
Application Number:
PCT/CN2021/096825
Publication Date:
December 01, 2022
Filing Date:
May 28, 2021
Export Citation:
Assignee:
UNIV DALIAN (CN)
International Classes:
C07C59/64; A61K31/192; A61P31/14; C07C51/43; C07C51/47; C07C51/48; C12P7/42; C12R1/645
Foreign References:
CN112741831A | 2021-05-04 | |||
CN112592327A | 2021-04-02 |
Other References:
ZHANG NASHA: "Endophytic Fungi from Rhodiola Sp. and Preliminary Study of Their Roles on Their Host's Growth and Development", MASTER THESIS, TIANJIN POLYTECHNIC UNIVERSITY, CN, no. 3, 15 March 2016 (2016-03-15), CN , XP093008725, ISSN: 1674-0246
LU XUAN ET AL.: "Quinones from Endophytic Fungus Fusarium sp. HJT-P-5 of Rhodiola Angusta Nakai", PHYTOCHEMISTRY LETTERS, vol. 39, 29 August 2020 (2020-08-29), XP086313993, ISSN: 1874-3900, DOI: 10.1016/j.phytol.2020.08.008
GUO HANG: "Secondary Metabolites from the Deep-Sea Derived Fungus Diaporthe Phaseolorum and Their Bioactivities", MASTER THESIS, TIANJIN POLYTECHNIC UNIVERSITY, CN, no. 2, 15 February 2020 (2020-02-15), CN , XP093008729, ISSN: 1674-0246
LU XUAN ET AL.: "Quinones from Endophytic Fungus Fusarium sp. HJT-P-5 of Rhodiola Angusta Nakai", PHYTOCHEMISTRY LETTERS, vol. 39, 29 August 2020 (2020-08-29), XP086313993, ISSN: 1874-3900, DOI: 10.1016/j.phytol.2020.08.008
GUO HANG: "Secondary Metabolites from the Deep-Sea Derived Fungus Diaporthe Phaseolorum and Their Bioactivities", MASTER THESIS, TIANJIN POLYTECHNIC UNIVERSITY, CN, no. 2, 15 February 2020 (2020-02-15), CN , XP093008729, ISSN: 1674-0246
Attorney, Agent or Firm:
DALIAN CHICCO PATENT OFFICE (CN)
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