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Title:
PREPARATION AND APPLICATION OF POLYKETONE COMPOUND HAVING ANTI-NOVEL CORONAVIRUS ACTIVITY
Document Type and Number:
WIPO Patent Application WO/2022/246810
Kind Code:
A1
Abstract:
A preparation method for a polyketone compound having anti-novel coronavirus activity, and an application of a polyketone compound. Solid fermentation is performed on alternaria endophytic fungi Alternaria sp., and a polyketone monomeric compound is obtained from a fermented product by using a series of separation and purification methods. The compound has the structure as represented by formula (I), and has anti-novel coronavirus activity.

Inventors:
LU XUAN (CN)
TANG XIAOYUAN (CN)
QI JUNKAI (CN)
FENG BAOMIN (CN)
TANG CHUAN (CN)
FENG WEIXING (CN)
Application Number:
PCT/CN2021/096825
Publication Date:
December 01, 2022
Filing Date:
May 28, 2021
Export Citation:
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Assignee:
UNIV DALIAN (CN)
International Classes:
C07C59/64; A61K31/192; A61P31/14; C07C51/43; C07C51/47; C07C51/48; C12P7/42; C12R1/645
Foreign References:
CN112741831A2021-05-04
CN112592327A2021-04-02
Other References:
ZHANG NASHA: "Endophytic Fungi from Rhodiola Sp. and Preliminary Study of Their Roles on Their Host's Growth and Development", MASTER THESIS, TIANJIN POLYTECHNIC UNIVERSITY, CN, no. 3, 15 March 2016 (2016-03-15), CN , XP093008725, ISSN: 1674-0246
LU XUAN ET AL.: "Quinones from Endophytic Fungus Fusarium sp. HJT-P-5 of Rhodiola Angusta Nakai", PHYTOCHEMISTRY LETTERS, vol. 39, 29 August 2020 (2020-08-29), XP086313993, ISSN: 1874-3900, DOI: 10.1016/j.phytol.2020.08.008
GUO HANG: "Secondary Metabolites from the Deep-Sea Derived Fungus Diaporthe Phaseolorum and Their Bioactivities", MASTER THESIS, TIANJIN POLYTECHNIC UNIVERSITY, CN, no. 2, 15 February 2020 (2020-02-15), CN , XP093008729, ISSN: 1674-0246
Attorney, Agent or Firm:
DALIAN CHICCO PATENT OFFICE (CN)
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