Title:
PREPARATION AND APPLICATION OF WEE1 KINASE INHIBITOR
Document Type and Number:
WIPO Patent Application WO/2023/179196
Kind Code:
A1
Abstract:
Disclosed are a preparation and application of a Wee1 kinase inhibitor, particularly relating to a compound as shown in formula (I) or formula (II) and a pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising the compound and/or the pharmaceutically acceptable salt thereof, and a use of the compound or the pharmaceutically acceptable salt thereof in the application of a medicament for the treatment or prevention of Wee1 kinase-associated diseases, especially tumors, wherein the compound is in a class of heterocyclic compounds. Also disclosed is a preparation method for the pharmaceutical composition of the compound or the pharmaceutically acceptable salt thereof. Substituents in the general formula (I) or formula (II) are the same as those defined in the description.
Inventors:
LIANG YONGHONG (CN)
XU ZHIYONG (CN)
ZENG ZHAOSEN (CN)
XIONG FANGJUN (CN)
XU ZHIYONG (CN)
ZENG ZHAOSEN (CN)
XIONG FANGJUN (CN)
Application Number:
PCT/CN2023/073788
Publication Date:
September 28, 2023
Filing Date:
January 30, 2023
Export Citation:
Assignee:
YA THERAPEUTICS INC (CN)
International Classes:
C07D471/04; A61K31/397; A61K31/496; A61K31/519; A61K31/551; A61P35/00; A61P35/02; C07D487/04; C07D487/14; C07D519/00
Foreign References:
| CN114591334A | 2022-06-07 | |||
| US20110245229A1 | 2011-10-06 | |||
| CN104011049A | 2014-08-27 | |||
| CN105829315A | 2016-08-03 | |||
| CN103703005A | 2014-04-02 | |||
| CN112442049A | 2021-03-05 | |||
| CN101432284A | 2009-05-13 |
Attorney, Agent or Firm:
SHENZHEN ZHONGZHI LICHENG PATENT AGENCY FIRM (CN)
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