PREPARATION OF AROMATIC-SUBSTITUTED SILYLAMINES BY THE DEHYDROGENATIVE COUPLING OF AROMATIC-SUBSTITUTED AMINE N-H AND SI-H BONDS

Title:

PREPARATION OF AROMATIC-SUBSTITUTED SILYLAMINES BY THE DEHYDROGENATIVE COUPLING OF AROMATIC-SUBSTITUTED AMINE N-H AND SI-H BONDS

Document Type and Number:

WIPO Patent Application WO/2019/140051

Kind Code:

A1

Abstract:

The present disclosure is directed at methods of forming an N-Si silyl bond, the method comprising contacting an organic substrate comprising an aromatic amine having at least one N- H bond with a mixture comprising of (a) at least one hydrosilane or hydrosiloxane and (b) at least one hydroxide or alkoxide, under conditions sufficient to form the N-Si bond. The disclosure is further directed to the compositions involved in these methods and the products that result therefrom.

Inventors:

TOUTOV ANTON (US)
BETZ KERRY (US)
ROMINE ANDREW (US)
GRUBBS ROBERT (US)

Application Number:

PCT/US2019/012991

Publication Date:

July 18, 2019

Filing Date:

January 10, 2019

Export Citation:

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Assignee:

CALIFORNIA INST OF TECHN (US)

International Classes:

C07F7/10

Foreign References:

US20160046653A1	2016-02-18
US20160176772A1	2016-06-23
US20140094607A1	2014-04-03

Other References:

QIN, Y. ET AL.: "Friede-Crafts-Type Intermolecular C-H Silylation of Electron-Rich Arenes Initiated by Base-Metal Salts", ANGEW. CHEM. INT. ED., vol. 55, no. 9, 24 February 2016 (2016-02-24), pages 3204 - 3207, XP055625622
KONIGS, C. D. F. ET AL.: "Catalytic dehydrogenative Si-N coupling of pyrroles, indoles, carbazoles as well as anilines with hydrosilanes without added base", CHEM. COMMUN., vol. 49, no. 15, 2013, pages 1506 - 1508, XP055625624

Attorney, Agent or Firm:

MURPHY, John, F. et al. (US)

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