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Patent Searching and Data


Title:
PREPARATION, COMPRISING INCLUSION COMPLEX OF VARENICLINE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, FOR ORAL ADMINISTRATION
Document Type and Number:
WIPO Patent Application WO/2018/160043
Kind Code:
A1
Abstract:
The present invention relates to a pharmaceutical preparation for oral administration, the pharmaceutical preparation comprising an inclusion complex formed by including varenicline or a pharmaceutically acceptable salt thereof in cyclodextrin. The pharmaceutical preparation can improve the convenience of administration by effectively blocking the bitter taste of a drug and the irritation in swallowing a drug, can be expected to have a stabilizing effect in view of oxidation stability of varenicline, and can improve the solubility of a drug.

Inventors:
JEON HONG RYEOL (KR)
KWON DO-WOO (KR)
LEE BONG-SANG (KR)
MEANG SEUL KI (KR)
PARK SU-JUN (KR)
KWAK SEONG-SHIN (KR)
Application Number:
PCT/KR2018/002551
Publication Date:
September 07, 2018
Filing Date:
March 02, 2018
Export Citation:
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Assignee:
CTC BIO INC (KR)
International Classes:
A61K9/00; A61K9/08; A61K9/16; A61K31/55; A61K47/12; A61K47/40
Domestic Patent References:
WO2010143070A22010-12-16
WO2006040680A12006-04-20
WO2009080021A12009-07-02
WO2009007768A12009-01-15
WO1999035131A11999-07-15
WO2001062736A12001-08-30
Foreign References:
EP2233134A12010-09-29
KR20110071008A2011-06-27
KR20040079012A2004-09-14
KR20090033330A2009-04-02
JP2006528237A2006-12-14
KR20170027790A2017-03-10
KR20170027791A2017-03-10
US6410550B12002-06-25
Other References:
EBBERT. J. O. ET AL.: "Effect of Varenicline on Smoking Cessation through Smoking Reduction: a Randomized Clinical Trial", JAMA, vol. 313, no. 7, 2015, pages 687 - 694, XP055552951
See also references of EP 3590498A4
Attorney, Agent or Firm:
PHIL & ONZI INT'L PATENT & LAW FIRM (KR)
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