Title:
PREPARATION OF GEMCITABINE AND INTERMEDIATES THEREOF
Document Type and Number:
WIPO Patent Application WO/2010/049947
Kind Code:
A3
Abstract:
The present patent application relates to a process for the preparation gemcitabine or a salt thereof. More particularly it relates to preparation of 3,5- dihydroxy protected -2-deoxy-2,2-difluoro -1-oxoribose, an intermediate used in the preparation of gemcitabine and its salts by using cyclohexylidene or cyclopentylidene protecting group, with high yield and purity.
Inventors:
NALINI MOHAN REDDY DODLE (IN)
SUDHIR RAVULAPALLI (IN)
SANJEEVA REDDY KUNDURU (IN)
SUDHIR RAVULAPALLI (IN)
SANJEEVA REDDY KUNDURU (IN)
Application Number:
PCT/IN2009/000602
Publication Date:
April 14, 2011
Filing Date:
October 26, 2009
Export Citation:
Assignee:
ACCRETE PHARMACEUTICAL PRIVATE LTD (IN)
NALINI MOHAN REDDY DODLE (IN)
SUDHIR RAVULAPALLI (IN)
SANJEEVA REDDY KUNDURU (IN)
NALINI MOHAN REDDY DODLE (IN)
SUDHIR RAVULAPALLI (IN)
SANJEEVA REDDY KUNDURU (IN)
International Classes:
C07H5/02
Domestic Patent References:
| WO2005095430A1 | 2005-10-13 |
Foreign References:
| US4808614A | 1989-02-28 | |||
| EP0805158A2 | 1997-11-05 |
Other References:
DATABASE CAPLUS ACS; 2011, accession no. STN Database accession no. 1991:142684
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