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Title:
PREPARATION OF INTERMEDIATES OF BOCEPREVIR
Document Type and Number:
WIPO Patent Application WO/2013/190509
Kind Code:
A3
Abstract:
Processes for preparing intermediates of Boceprevir and their use in preparation of Boceprevir or its pharmaceutically acceptable salts are provided.

Inventors:
NARIYAM, Sekhar Munaswamy (Flat No.212, Maruthi estates Nagarjuna Homes,Nizampet Road, Kukatpally, Hyderabad 2, 50007, IN)
BHALERAO, Dinesh Shivaji (F-107, SMR Metropolis,Miyapur, AndhraPradesh,India, Hyderabad 9, 50004, IN)
DAHANUKAR, Vilas Hareshwar (Plot no-11, Lalitha Bloomfield Nanakramguda,Next to Oakridge School,,Andhra Pradesh, India, Hyderabad 8, 50000, IN)
ORUGANTI, Srinivas (404 Sai Sri Apartments, Camelot Layout,Kondapur, Andhra Pradesh, India, Hyderabad 2, 50003, IN)
RAPOLU, Rajesh Kumar (Flat No 101, Raghavendra Homes Cherukuthota colony,Saroor nagar, Andhra Pradesh, Hyderabad 5, 50003, IN)
KANDAGATLA, Bhaskar (H.NO: 2-2-129/102, Pushpa EnclaveVijayapuri Colony, Uppal,Andhra Pradesh, India, Hyderabad 9, 50003, IN)
IQBAL, Javed (48 Villa Greens, Gandipet Andhra Pradesh, India, Hyderabad 5, 50007, IN)
KHOBARE, Sandip Ramdas (At/Post - Ghospuri, Taluka & DistrictMaharashtra, India, Ahmednagar 5, 41400, IN)
KALLAM, Srinivasa Reddy (H.No: 1-7, Pulluru Post,Mylavaram Mandal,Andhrapradesh, India, Vijaywada 0, 52123, IN)
BANDA, Malavika (IC-240, Errammanzil Colony Panjagutta,Andhrapradesh, India, Hyderabad 2, 50008, IN)
GARARE, Vikas Sadashiv (G Plot No-70, Prasanna najaneya Nillayam,ASR nagar, Miyapur, Hyderabad 9, 50004, IN)
EDA, Vishnuvardhana vema Reddy (Plot No-1021, Srivijayadurga ResidenceHMT Swarnapuri colony,Miyapur, Andhra Pradesh, India, Hyderabad 9, 50004, IN)
Application Number:
IB2013/055096
Publication Date:
March 13, 2014
Filing Date:
June 21, 2013
Export Citation:
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Assignee:
DR.REDDYS LABORATORIES LIMITED (8-2-337, Road No. 3Banjara hills,,Andhra Pradesh, India, Hyderabad 4, 50003, IN)
International Classes:
C07C273/18; A61K31/401; A61P31/00; C07C275/16; C07D209/52; C07K5/08
Domestic Patent References:
WO2008064066A12008-05-29
WO2009039361A22009-03-26
Foreign References:
US20100256416A12010-10-07
JPS60155967A1985-08-16
Other References:
DANOPOULOS,ANDREAS ET AL.: 'Synthesis of Isocyanates by the Reaction of Certain Primary Amines with Benzyl Carbonochloridate' SYNTHESIS 1985, page 682
AVDEENKO,A. P. ET AL.: 'Synthesis and Structure ofN-Alkyl(aryl)aminocarbonyl-1,4- benzoquinone Imines.' RUSSIAN JOUMAL OF ORGANIC CHEMISTRY vol. 44, no. 12, December 2008, pages 1765 - 1772
SAYLIK, DILEK ET AL.: 'Preparation of Isocyanates from Primary Amines and Carbon Dioxide Using Mitsunobu Chemistry.' J. ORG. CHEM. vol. 64, no. 11, 07 May 1999, pages 3940 - 3946
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