Title:
PREPARATION METHOD OF ANTIBACTERIAL OXAZOLIDINONE MEDICINE AND INTERMEDIATE THEREOF
Document Type and Number:
WIPO Patent Application WO/2017/201846
Kind Code:
A1
Abstract:
A preparation method of an antibacterial oxazolidinone medicine and an intermediate thereof. The preparation method avoids using explosive azide compounds and allergenic and genotoxic chlorides, and avoids a column chromatography purification method which cannot be performed in industrialized production, the preparation method comprises mild and safe reaction conditions, simple process steps, and is suitable for large-scale industrialized production. In this invention, M is H, or an alkali metal, an alkali earth metal or a basic amino acid pharmaceutically acceptable salt.
Inventors:
ZHAO SHENGXIAN (CN)
ZHU FANGMENG (CN)
ZHAO NENGXUAN (CN)
LI KUN (CN)
MA XIANGHONG (CN)
CHU JIEGEN (CN)
FU LINGYAN (CN)
CAO ZHEJUN (CN)
ZHU FANGMENG (CN)
ZHAO NENGXUAN (CN)
LI KUN (CN)
MA XIANGHONG (CN)
CHU JIEGEN (CN)
FU LINGYAN (CN)
CAO ZHEJUN (CN)
Application Number:
PCT/CN2016/090282
Publication Date:
November 30, 2017
Filing Date:
July 18, 2016
Export Citation:
Assignee:
ZHEJIANG APELOA TOSPO PHARMACEUTICAL CO LTD (CN)
YOSEMADE PHARMACEUTICAL CO LTD (CN)
YOSEMADE PHARMACEUTICAL CO LTD (CN)
International Classes:
C07D413/04; C07D213/61; C07D498/04; C07F9/09
Foreign References:
| CN103896963A | 2014-07-02 | |||
| CN102099355A | 2011-06-15 | |||
| CN104592337A | 2015-05-06 | |||
| CN101365689A | 2009-02-11 |
Attorney, Agent or Firm:
HANGZHOU TIANQIN INTELLECTUAL PROPERTY AGENCY CO., LTD. (CN)
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