PREPARATION METHOD AND APPLICATION OF DOUBLE-ELECTRIC-FIELD DRIVING SENSOR

WIPO Patent Application WO/2023/212991

A1

A preparation method and application of a double-electric-field driving sensor. A flexible printed substrate is manufactured by adopting a flexible printed circuit technology, and double-electric-field distribution is effectively adjusted by using a plurality of electrode arrays on the flexible printed electrode. The sensor is endowed with good biocompatibility, catalytic performance and conductivity by modifying RGO and gold nanoparticles on the surface of the electrode. Moreover, a pesticide antibody is introduced to selectively identify pesticide molecules, microflow and particles in a solution can directionally move under the condition of external double-electric-field driving, and an analyte can quickly flow to the surface of a biosensor, such that the binding efficiency of the analyte and a probe on the surface of the sensor is improved, and the reaction time is shortened. The complementary double-electric-field mode can effectively prevent bubbles from being generated on the surface of the sensor due to overlarge voltage, such that a more effective electric field enhancement strategy is established, and the sensitivity and the detection efficiency of the sensor are improved.

ZHANG WEN (CN)
SU XIAOYU (CN)
YUAN LEI (CN)
ZHOU XUAN (CN)
HU JUTAO (CN)
ZOU XIAOBO (CN)

PCT/CN2022/095898

November 09, 2023

May 30, 2022

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UNIV JIANGSU (CN)

G01N27/48; G01N27/327

CN113970585A	2022-01-25
CN111841468A	2020-10-30
US20120034684A1	2012-02-09
US20200173890A1	2020-06-04

NANJING DOYES INTELLECTUAL PROPERTY CO., LTD. (CN)

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