Title:
PREPARATION METHOD OF DIHYDROINDENE AMIDE COMPOUNDS，THEIR PHARMACEUTICAL COMPOSITIONS CONTAING COMPOUNDS THEREOF AND USE AS PROTEIN KINASES INHIBITOR
Document Type and Number:
WIPO Patent Application WO/2010/072166
Kind Code:
A1
Abstract:
The invention provides a new kind of dihydroindene amide compounds of general formula I or their pharmaceutically acceptable salts or prodrug thereof which can be used as protein kinase inhibitor. The invention provides a preparation method of the kind of compounds, the pharmaceutical compositions containing the compounds, the method for preventing or curing the diseases related to the abnormity of activities of protein kinases, especially Abl, Bcr-Abl, c-Kit and PDGFR, using them as protein kinase inhibitor, and their preparation use of drug used for preventing or curing the diseases related to the abnormity of activities of protein kinases, especially Abl, Bcr-Abl, c-Kit and PDGFR.
Inventors:
YANG, Xuqing (Room 416 No.2 Building, 18 Anning Village East Road Haidian District, Beijing 5, 100085, CN)
杨旭清 (中国北京市海淀区清河安宁庄东路18号2号办公楼416室, Beijing 5, 100085, CN)
XUE, Long (Room 416 No.2 Building, 18 Anning Village East Road Haidian District, Beijing 5, 100085, CN)
杨旭清 (中国北京市海淀区清河安宁庄东路18号2号办公楼416室, Beijing 5, 100085, CN)
XUE, Long (Room 416 No.2 Building, 18 Anning Village East Road Haidian District, Beijing 5, 100085, CN)
Application Number:
CN2009/076006
Publication Date:
July 01, 2010
Filing Date:
December 24, 2009
Export Citation:
Assignee:
BEIJING MEDESIGNPHARMA CO., LTD. (Room 416 No.2 Building, 18 Anning Village East Road Haidian District, Beijing 5, 100085, CN)
北京美迪赛医药技术有限公司 (中国北京市海淀区清河安宁庄东路18号2号办公楼416室, Beijing 5, 100085, CN)
YANG, Xuqing (Room 416 No.2 Building, 18 Anning Village East Road Haidian District, Beijing 5, 100085, CN)
杨旭清 (中国北京市海淀区清河安宁庄东路18号2号办公楼416室, Beijing 5, 100085, CN)
北京美迪赛医药技术有限公司 (中国北京市海淀区清河安宁庄东路18号2号办公楼416室, Beijing 5, 100085, CN)
YANG, Xuqing (Room 416 No.2 Building, 18 Anning Village East Road Haidian District, Beijing 5, 100085, CN)
杨旭清 (中国北京市海淀区清河安宁庄东路18号2号办公楼416室, Beijing 5, 100085, CN)
International Classes:
C07C233/64; A61K31/16; A61P9/00; A61P9/10; A61P17/06; A61P27/00; A61P29/00; A61P35/00; A61P35/02
Attorney, Agent or Firm:
KANGXIN PARTNERS, P.C. (Floor 16, Tower AIndo Building,A48 Zhichun Road, Haidian District, Beijing 8, 100098, CN)
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