Title:
PREPARATION METHOD OF HYALURONIC ACID MICROBEADS AND USE OF HYALURONIC ACID MICROBEADS
Document Type and Number:
WIPO Patent Application WO/2019/221432
Kind Code:
A1
Abstract:
The present invention relates to a method for preparing hyaluronic acid microbeads and a use of the hyaluronic acid microbeads. More specifically, the present invention relates to a method for preparing hyaluronic acid microbeads, the method comprising crosslinking hyaluronic acid with one or more ligands selected from the group consisting of alendronate (ALD), adenosine diphosphate (ADP), and adenosine triphosphate (ATP). The hyaluronic microbeads according to the present invention have desirable biocompatibility, biodegradability, and physical stability, and thus may be applied for various uses, for example, as a dental filling material, an orthopedic support material, a cosmetic filler, an anti-adhesive agent, a cell scaffold, and a drug carrier.
Inventors:
CHOI WON IL (KR)
Application Number:
PCT/KR2019/005355
Publication Date:
November 21, 2019
Filing Date:
May 03, 2019
Export Citation:
Assignee:
KOREA INST CERAMIC ENG & TECH (KR)
International Classes:
C08J3/12; C08J3/24; C08L5/08
Foreign References:
| KR20040018927A | 2004-03-04 | |||
| KR20130109130A | 2013-10-07 | |||
| KR20080073419A | 2008-08-11 |
Other References:
NEGI, LALIT MOHAN ET AL.: "Surface engineered nanostructured lipid carriers for targeting MDR tumor: Part 1. Synthesis, characterization and in vitro investigation", COLLOIDS AND SURFACES B: BIOINTERFACES, vol. 123, 27 October 2014 (2014-10-27), pages 600 - 609, XP029106664
SHI, LIYANG ET AL.: "Dynamic coordination chemistry enables free directional printing of biopolymer hydrogel", CHEMISTRY OF MATERIALS, vol. 29, no. 14, 14 June 2017 (2017-06-14), pages 5816 - 5823, XP055653656
SHI, LIYANG ET AL.: "Dynamic coordination chemistry enables free directional printing of biopolymer hydrogel", CHEMISTRY OF MATERIALS, vol. 29, no. 14, 14 June 2017 (2017-06-14), pages 5816 - 5823, XP055653656
Attorney, Agent or Firm:
KIM, Tae Sun (KR)
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