Title:
PREPARATION METHOD FOR LENALIDOMIDE DERIVATIVE AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/091046
Kind Code:
A1
Abstract:
The present invention discloses a lenalidomide derivative, a preparation method therefor, and an application thereof. The lenalidomide derivative provided by the present invention has a structural formula as shown in formula I. The lenalidomide derivative of formula I provided by the present invention has obvious anti-inflammatory action and no neurotoxicity, and has good application prospects in the field of design and development of anti-inflammatory drugs. Further, the compound also has an obvious anti-cancer effect, and has good application prospects in the research and development of anti-cancer drugs.
Inventors:
WANG WEI (CN)
WANG YANDONG (CN)
WANG HONGTAO (CN)
LU YONGZHANG (CN)
YAN JIANHUI (CN)
WANG YANDONG (CN)
WANG HONGTAO (CN)
LU YONGZHANG (CN)
YAN JIANHUI (CN)
Application Number:
PCT/CN2018/082738
Publication Date:
May 16, 2019
Filing Date:
April 12, 2018
Export Citation:
Assignee:
GUANGDONG ZHONGKE MEDICIN R & D LTD (CN)
International Classes:
C07D209/46; A61K31/4035; A61K31/5377; A61P29/00; A61P35/00; A61P35/02
Foreign References:
| CN1802353A | 2006-07-12 | |||
| US5698579A | 1997-12-16 | |||
| EP1477486A2 | 2004-11-17 | |||
| CN101074210A | 2007-11-21 | |||
| CN1413211A | 2003-04-23 | |||
| CN107698484A | 2018-02-16 |
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