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Title:
PREPARATION METHOD FOR VELPATASVIR INTERMEDIATE AND ANALOGUE THEREOF
Document Type and Number:
WIPO Patent Application WO/2018/103239
Kind Code:
A1
Abstract:
Disclosed is a preparation method for a compound shown by formula (E), a Velpatasvir intermediate shown by formula (K) and an analogue thereof. The method of the present invention uses inexpensive and easily available materials, and a simple process operation, without the need for separating the intermediates, the products are by column chromatography, and it is suitable for industrialized large-scale production..

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Inventors:
WU CHENGLONG (CN)
ZENG WEN (CN)
LIU SHAOLI (CN)
GONG JIAFU (CN)
HUANG JINKUN (CN)
XIE DEJIAN (CN)
Application Number:
PCT/CN2017/078589
Publication Date:
June 14, 2018
Filing Date:
March 29, 2017
Export Citation:
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Assignee:
XILING LAB CO LTD (CN)
International Classes:
C07C221/00; C07C225/22; C07D311/78
Foreign References:
CN102056894A2011-05-11
CN105712969A2016-06-29
CN105732563A2016-07-06
Attorney, Agent or Firm:
GAOYUNG INTELLECTUAL PROPERTY AGENCY (GENERAL PARTNERSHIP) (CN)
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