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Title:
PREPARATION AND USE OF MACROCYCLIC HETEROCYCLIC COMPOUND AS EGFR INHIBITOR
Document Type and Number:
WIPO Patent Application WO/2024/078263
Kind Code:
A1
Abstract:
The present invention relates to a macrocyclic heterocyclic compound as a selective inhibitor of a clinical mutant of EGFR kinase, and specifically relates to a compound represented by formula I or a pharmaceutically acceptable salt thereof, a stereoisomer thereof or a tautomer thereof, a preparation method therefor, a pharmaceutical composition containing same, and a medical use thereof.

Inventors:
LIANG YONGHONG (CN)
Application Number:
PCT/CN2023/119243
Publication Date:
April 18, 2024
Filing Date:
September 15, 2023
Export Citation:
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Assignee:
YA THERAPEUTICS INC (CN)
International Classes:
C07D498/22; A61K31/439; A61P35/00; C07D487/04; C07D487/22
Domestic Patent References:
WO2022166741A12022-08-11
WO2009112439A12009-09-17
Foreign References:
CN114007698A2022-02-01
CN1675225A2005-09-28
CN113735856A2021-12-03
CN106164075A2016-11-23
CN114907379A2022-08-16
CN115073469A2022-09-20
Attorney, Agent or Firm:
SHENZHEN ANYMEN PATENT AGENCY (GENERAL PARTNERSHIP) 91440300MA5GNMBB68 et al. (CN)
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