Title:
PREPARATION AND USE OF PHENYLQUINOLINONE AND FLAVONOID DERIVATIVES
Document Type and Number:
WIPO Patent Application WO/2018/233483
Kind Code:
A1
Abstract:
Provided are phenylquinolinone and flavonoid derivatives and preparation methods therefor, wherein the derivatives are histamine H3 receptor antagonists, which can protect and restore the normal function of the central nervous system; and in particular provided is the use thereof in neurodegenerative disease and ischemic brain injury. The phenylquinolinone and flavonoid derivatives have great clinical application value.
Inventors:
SHENG RONG (CN)
LOU JINFANG (CN)
YAN HONGBING (CN)
HU YONGZHOU (CN)
TANG LI (CN)
ZHANG FENGMIN (CN)
LOU JINFANG (CN)
YAN HONGBING (CN)
HU YONGZHOU (CN)
TANG LI (CN)
ZHANG FENGMIN (CN)
Application Number:
PCT/CN2018/089970
Publication Date:
December 27, 2018
Filing Date:
June 05, 2018
Export Citation:
Assignee:
HANGZHOU BIO SINCERITY PHARMA TECH CO LTD (CN)
International Classes:
C07D215/233; A61K31/352; A61K31/4709; A61P25/00; A61P25/08; A61P25/16; A61P25/28; C07D311/30; C07D311/60; C07D311/62
Domestic Patent References:
| WO2009097306A1 | 2009-08-06 |
Foreign References:
| CN103929959A | 2014-07-16 | |||
| CN1960977A | 2007-05-09 | |||
| CN101522638A | 2009-09-02 | |||
| CN103087024A | 2013-05-08 | |||
| CN1326450A | 2001-12-12 | |||
| CN103588702A | 2014-02-19 |
Attorney, Agent or Firm:
HANGZHOU QIUSHI PATENT OFFICE CO., LTD. (CN)
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