Title:
PRESERVATIVE FOR CRYOPRESERVATION OF BIOLOGICAL MATERIALS AND METHOD FOR PRESERVING BIOLOGICAL MATERIALS AT LOW TEMPERATURE
Document Type and Number:
WIPO Patent Application WO/2014/162910
Kind Code:
A1
Abstract:
Disclosed are: a preservative for cryopreservation of biological materials, containing a flavonoid compound represented by formula (I) (in the formula, R1-R9 are the same or different, and are -H, -OH, or an alkoxy group) and a flavonoid glycoside compound represented by formula (II) (in the formula, R10 and R11 are -H, -OH, or glucose residue, and at least one is glucose residue; and R12-R18 are the same or different, and are -H, -OH, or an alkoxy group); a preservative solution; and a method for preserving biological materials.
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Inventors:
KATO FUMINORI (JP)
FUJIKAWA SEIZO (JP)
MOTOMURA NOBORU (JP)
SAITO AYA (JP)
SHIMADA SHOGO (JP)
OZAKI SHINNICHI (JP)
FUJIKAWA SEIZO (JP)
MOTOMURA NOBORU (JP)
SAITO AYA (JP)
SHIMADA SHOGO (JP)
OZAKI SHINNICHI (JP)
Application Number:
PCT/JP2014/058108
Publication Date:
October 09, 2014
Filing Date:
March 24, 2014
Export Citation:
Assignee:
ISHIHARA SANGYO KAISHA (JP)
UNIV TOKYO (JP)
UNIV TOKYO (JP)
International Classes:
C12N5/07; A01N1/02; A01N3/02; A01N43/16; A23B4/08; A23B7/14; C12N5/04
Domestic Patent References:
| WO2008007684A1 | 2008-01-17 | |||
| WO2014010685A1 | 2014-01-16 | |||
| WO2013047666A1 | 2013-04-04 | |||
| WO2013047665A1 | 2013-04-04 |
Foreign References:
| JP2009219395A | 2009-10-01 | |||
| JP2009221128A | 2009-10-01 |
Other References:
AHLENSTIEL T. ET AL.: "Improved cold preservation of kidney tubular cells by means of adding bioflavonoids to organ preservation solutions", TRANSPLANTATION, vol. 81, no. 2, 2006, pages 231 - 239
AHLENSTIEL T. ET AL.: "Bioflavonoids attenuate renal proximal tubular cell injury during cold preservation in Euro-Collins and University of Wisconsin solutions", KIDNEY INT., vol. 63, no. 2, 2003, pages 554 - 563
NAKAZAWA F. ET AL.: "Improvement of preserving hepatocyte in new method for the therapy of hepatocyte transplantation", ORGAN BIOL., vol. 16, no. 1, 2009, pages 74
FUMINORI KATO ET AL.: "Teion Joken de Yudo sareru Saibo Shogai ni Taisuru Flavonoid Haitotai no Hogo Sayo", DAI 58 KAI JAPANESE SOCIETY FOR CRYOBIOLOGY AND CRYOTECHNOLOGY SEMINAR NENKAI KOEN YOSHI, June 2013 (2013-06-01), pages 42
SHIMADA S. ET AL.: "The effect of supercoolant, Kaempferol 7-o-glucoside, heterotopic rat heart transplantation model", DAI 36 KAI JAPAN SOCIETY FOR LOW TEMPERATURE MEDICINE SOKAI, 2009, pages 41
AHLENSTIEL T. ET AL.: "Bioflavonoids attenuate renal proximal tubular cell injury during cold preservation in Euro-Collins and University of Wisconsin solutions", KIDNEY INT., vol. 63, no. 2, 2003, pages 554 - 563
NAKAZAWA F. ET AL.: "Improvement of preserving hepatocyte in new method for the therapy of hepatocyte transplantation", ORGAN BIOL., vol. 16, no. 1, 2009, pages 74
FUMINORI KATO ET AL.: "Teion Joken de Yudo sareru Saibo Shogai ni Taisuru Flavonoid Haitotai no Hogo Sayo", DAI 58 KAI JAPANESE SOCIETY FOR CRYOBIOLOGY AND CRYOTECHNOLOGY SEMINAR NENKAI KOEN YOSHI, June 2013 (2013-06-01), pages 42
SHIMADA S. ET AL.: "The effect of supercoolant, Kaempferol 7-o-glucoside, heterotopic rat heart transplantation model", DAI 36 KAI JAPAN SOCIETY FOR LOW TEMPERATURE MEDICINE SOKAI, 2009, pages 41
Attorney, Agent or Firm:
SAEGUSA & PARTNERS (JP)
Patent business corporation 3 Edakuni [Hajime] patent firm (JP)
Patent business corporation 3 Edakuni [Hajime] patent firm (JP)
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