Title:
PRESERVED FUSOGENIC VESICLES
Document Type and Number:
WIPO Patent Application WO2006028786
Kind Code:
A3
Abstract:
Preserved fusogenic vesicles are disclosed that include a saccharide, a fusogen, and a first polar phospholipid that is a stable vesicle former. The preserved fusogenic vesicles have a fusion rate of at least (20) vesicle fusions per second when re-hydrated. Methods of preserving fusogenic vesicles also are disclosed. Unexpectedly, after re-rehydration the preserved fusogenic vesicles may transfer substantially more ATP through a cell membrane than unpreserved fusogenic vesicles.
Inventors:
EHRINGER WILLIAM D (US)
Application Number:
PCT/US2005/030728
Publication Date:
August 10, 2006
Filing Date:
August 30, 2005
Export Citation:
Assignee:
UNIV LOUISVILLE RES FOUND (US)
EHRINGER WILLIAM D (US)
EHRINGER WILLIAM D (US)
International Classes:
A61K9/127
Foreign References:
| US6417326B1 | 2002-07-09 | |||
| US5939096A | 1999-08-17 |
Other References:
ARAKAWA A. ET AL.: "Preparation of liposome-encapsulating Adenosine Triphosphate", TOHOKU J. EXP. MED., vol. 184, 1998, pages 39 - 47, XP002611450
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