Title:
PREVENTING OR MITIGATING CHEMOTHERAPY INDUCED ALOPECIA USING VITAMIN D
Document Type and Number:
WIPO Patent Application WO/2017/214064
Kind Code:
A8
Abstract:
The invention provides methods and pharmaceutical compositions for preventing or mitigating chemotherapy-induced alopecia (CIA). The pharmaceutical compositions of the invention comprise an effective amount of a vitamin D compound in a topical formulation. The invention has broad applications in chemotherapies that induce alopecia, for example taxane based chemotherapy for cervical cancer, endometrial cancer, ovarian cancer, fallopian tube cancer, primary peritoneal carcinoma, soft tissue sarcoma, or bone sarcoma. The pharmaceutical compositions of the invention can be advantageously administered before and/or concurrent with the chemotherapy.
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Inventors:
SARANGARAJAN RANGAPRASAD (US)
JIMENEZ JOAQUIN J (US)
NARAIN NIVEN RAJIN (US)
JIMENEZ JOAQUIN J (US)
NARAIN NIVEN RAJIN (US)
Application Number:
PCT/US2017/036011
Publication Date:
January 11, 2018
Filing Date:
June 05, 2017
Export Citation:
Assignee:
BERG LLC (US)
International Classes:
A61K8/67; A61K31/593
Attorney, Agent or Firm:
MELLO, Jill, Ann et al. (US)
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