Title:
PREVENTION OF RETROGRADATION OF STARCH
Document Type and Number:
WIPO Patent Application WO2003002728
Kind Code:
A3
Abstract:
The invention provides an isolated or recombinant nucleic acid derived from a nucleic acid encoding a polypeptide essentially having alpha-glucanotransferase activity but having essentially no hydrolysing activity, said isolated or recombinant nucleic acid encoding a polypeptide with hydrolytic activity.
Inventors:
VAN DER MAAREL MARC JOS ELISE (NL)
DIJKHUIZEN LUBBERT (NL)
BINNEMA DOEVE JACOB (NL)
VAN DER VEEN BARTELE ANDRIES (NL)
VOS ARNOLD (NL)
DIJKHUIZEN LUBBERT (NL)
BINNEMA DOEVE JACOB (NL)
VAN DER VEEN BARTELE ANDRIES (NL)
VOS ARNOLD (NL)
Application Number:
PCT/NL2002/000427
Publication Date:
October 30, 2003
Filing Date:
July 01, 2002
Export Citation:
Assignee:
TNO (NL)
VAN DER MAAREL MARC JOS ELISE (NL)
DIJKHUIZEN LUBBERT (NL)
BINNEMA DOEVE JACOB (NL)
VAN DER VEEN BARTELE ANDRIES (NL)
VOS ARNOLD (NL)
VAN DER MAAREL MARC JOS ELISE (NL)
DIJKHUIZEN LUBBERT (NL)
BINNEMA DOEVE JACOB (NL)
VAN DER VEEN BARTELE ANDRIES (NL)
VOS ARNOLD (NL)
International Classes:
A21D8/04; C12N1/21; C12N9/10; (IPC1-7): C12N15/54; A21D8/04; C12N1/21; C12N9/10
Domestic Patent References:
| WO1998015347A1 | 1998-04-16 |
Foreign References:
| EP0884384A2 | 1998-12-16 |
Other References:
VAN DER VEEN BART A ET AL: "The role of arginine 47 in the cyclization and coupling reactions of cyclodextrin glycosyltransferase from Bacillus circulans strain 251: Implications for product inhibition and product specificity.", EUROPEAN JOURNAL OF BIOCHEMISTRY, vol. 267, no. 12, June 2000 (2000-06-01), pages 3432 - 3441, XP002244395, ISSN: 0014-2956
VAN DER VEEN BART A ET AL: "Rational design of cyclodextrin glycosyltransferase from Bacillus circulans strain 251 to increase alpha-cyclodextrin production.", JOURNAL OF MOLECULAR BIOLOGY., vol. 296, no. 4, 3 March 2000 (2000-03-03), pages 1027 - 1038, XP002244396, ISSN: 0022-2836
PRZYLAS INGO ET AL: "Crystal structure of amylomaltase from Thermus aquaticus, a glycosyltransferase catalysing the production of large cyclic glucans.", JOURNAL OF MOLECULAR BIOLOGY, vol. 296, no. 3, 25 February 2000 (2000-02-25), pages 873 - 886, XP002195371, ISSN: 0022-2836
TERADA YOSHINOBU ET AL: "Thermus aquaticus ATCC 33923 amylomaltase gene cloning and expression and enzyme characterization: Production of cycloamylose.", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 65, no. 3, March 1999 (1999-03-01), pages 910 - 915, XP002936112, ISSN: 0099-2240
VAN DER MAAREL M J E C ET AL: "Amylomaltase from the hyperthermophilic bacterium Thermus thermophilus: Enzyme characteristics and application in the starch industry.", MEDEDELINGEN FACULTEIT LANDBOUWKUNDIGE EN TOEGEPASTE BIOLOGISCHE, vol. 65, no. 3A, 2000, pages 231 - 234, XP001059063
DATABASE WPI Section Ch Week 200111, 21 November 2000 Derwent World Patents Index; Class D13, AN 2001-095337, XP002195372, TAKADA HIROKI ET AL: "preparation of a cyclic glucan by using a highly heat-resistant branching enzyme."
FUJIWARA SHINSUKE ET AL: "Analysis of mutations in cyclodextrin glucanotransferase from Bacillus stearothermophilus which affect cyclization characteristics and thermostability.", JOURNAL OF BACTERIOLOGY, vol. 174, no. 22, 1992, pages 7478 - 7481, XP001064682, ISSN: 0021-9193
LEEMHUIS HANS ET AL: "Mutations converting cyclodextrin glycosyltransferase from a transglycosylase into a starch hydrolase.", FEBS LETTERS, vol. 514, no. 2-3, 2002, 13 March, 2002, pages 189 - 192, XP002244397, ISSN: 0014-5793
VAN DER VEEN BART A ET AL: "Hydrophobic amino acid residues in the acceptor binding site are main determinants for reaction mechanism and specificity of cyclodextrin-glycosyltransferase.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 276, no. 48, 30 November 2001 (2001-11-30), November 30, 2001, pages 44557 - 44562, XP002244398, ISSN: 0021-9258
VAN DER VEEN BART A ET AL: "Rational design of cyclodextrin glycosyltransferase from Bacillus circulans strain 251 to increase alpha-cyclodextrin production.", JOURNAL OF MOLECULAR BIOLOGY., vol. 296, no. 4, 3 March 2000 (2000-03-03), pages 1027 - 1038, XP002244396, ISSN: 0022-2836
PRZYLAS INGO ET AL: "Crystal structure of amylomaltase from Thermus aquaticus, a glycosyltransferase catalysing the production of large cyclic glucans.", JOURNAL OF MOLECULAR BIOLOGY, vol. 296, no. 3, 25 February 2000 (2000-02-25), pages 873 - 886, XP002195371, ISSN: 0022-2836
TERADA YOSHINOBU ET AL: "Thermus aquaticus ATCC 33923 amylomaltase gene cloning and expression and enzyme characterization: Production of cycloamylose.", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 65, no. 3, March 1999 (1999-03-01), pages 910 - 915, XP002936112, ISSN: 0099-2240
VAN DER MAAREL M J E C ET AL: "Amylomaltase from the hyperthermophilic bacterium Thermus thermophilus: Enzyme characteristics and application in the starch industry.", MEDEDELINGEN FACULTEIT LANDBOUWKUNDIGE EN TOEGEPASTE BIOLOGISCHE, vol. 65, no. 3A, 2000, pages 231 - 234, XP001059063
DATABASE WPI Section Ch Week 200111, 21 November 2000 Derwent World Patents Index; Class D13, AN 2001-095337, XP002195372, TAKADA HIROKI ET AL: "preparation of a cyclic glucan by using a highly heat-resistant branching enzyme."
FUJIWARA SHINSUKE ET AL: "Analysis of mutations in cyclodextrin glucanotransferase from Bacillus stearothermophilus which affect cyclization characteristics and thermostability.", JOURNAL OF BACTERIOLOGY, vol. 174, no. 22, 1992, pages 7478 - 7481, XP001064682, ISSN: 0021-9193
LEEMHUIS HANS ET AL: "Mutations converting cyclodextrin glycosyltransferase from a transglycosylase into a starch hydrolase.", FEBS LETTERS, vol. 514, no. 2-3, 2002, 13 March, 2002, pages 189 - 192, XP002244397, ISSN: 0014-5793
VAN DER VEEN BART A ET AL: "Hydrophobic amino acid residues in the acceptor binding site are main determinants for reaction mechanism and specificity of cyclodextrin-glycosyltransferase.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 276, no. 48, 30 November 2001 (2001-11-30), November 30, 2001, pages 44557 - 44562, XP002244398, ISSN: 0021-9258
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