Title:
PREVENTION AND/OR TREATMENT OF EYE DISEASE BY COLLAGEN FIBER CROSSLINKING
Document Type and Number:
WIPO Patent Application WO/2022/019304
Kind Code:
A1
Abstract:
The present invention provides an improvement in the strength of the scleral by collagen fiber crosslinking via crosslinking treatment of the sclera at the equatorial region of the eye and/or at the posterior pole such as the fundus of the eye. Also provided is the prevention and/or treatment of eye disease by the same. Provided are: a photosensitizer used in a crosslinking treatment for the sclera at the equatorial region of the eye and/or at the posterior pole of the eye; a kit containing the same; and a method for emitting light for the crosslinking treatment.
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Inventors:
OHASHI KOJI (JP)
KOYAMA YUKIE (JP)
TANAKA YASUHISA (JP)
OKABE KOMEI (JP)
OGAWA TOSHIHIRO (JP)
KAMIKATANO MITSURU (JP)
KOYAMA YUKIE (JP)
TANAKA YASUHISA (JP)
OKABE KOMEI (JP)
OGAWA TOSHIHIRO (JP)
KAMIKATANO MITSURU (JP)
Application Number:
PCT/JP2021/027154
Publication Date:
January 27, 2022
Filing Date:
July 20, 2021
Export Citation:
Assignee:
SANTEN PHARMACEUTICAL CO LTD (JP)
FIBERTECH CO LTD (JP)
FIBERTECH CO LTD (JP)
International Classes:
A61K41/00; A61F9/007; A61K31/525; A61K31/661; A61K31/7084; A61K41/17; A61P27/10
Foreign References:
| JP2017514564A | 2017-06-08 | |||
| JP2015530202A | 2015-10-15 | |||
| US20210015664A1 | 2021-01-21 |
Other References:
KWOK SHELDON J. J., FORWARD SARAH, WERTHEIMER CHRISTIAN M., LIAPIS ANDREAS C., LIN HARVEY H., KIM MOONSEOK, SEILER THEO G., BIRNGR: "Selective Equatorial Sclera Crosslinking in the Orbit Using a Metal-Coated Polymer Waveguide", INVESTIGATIVE OPTHALMOLOGY & VISUAL SCIENCE, ASSOCIATION FOR RESEARCH IN VISION AND OPHTHALMOLOGY, US, vol. 60, no. 7, 18 June 2019 (2019-06-18), US , pages 2563, XP055901256, ISSN: 1552-5783, DOI: 10.1167/iovs.19-26709
ISELI HANS PETER; KöRBER NICOLE; KOCH CHRISTIAN; KARL ANETT; PENK ANJA; HUSTER DANIEL; REICHENBACH ANDREAS; WIEDEMANN PETER; : "Scleral cross-linking by riboflavin and blue light application in young rabbits: damage threshold and eye growth inhibition", GRAEFE'S ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, SPRINGER BERLIN HEIDELBERG, BERLIN/HEIDELBERG, vol. 254, no. 1, 23 November 2015 (2015-11-23), Berlin/Heidelberg, pages 109 - 122, XP035880082, ISSN: 0721-832X, DOI: 10.1007/s00417-015-3213-x
J CATARACT REFRACT SURG, vol. 30, 2004, pages 689 - 695
ACTA OPHTHALMOL, vol. 87, 2009, pages 193 - 198
J CATARACT REFRACT SURG, vol. 39, 2013, pages 1184 - 1189
J CATARACT REFACT SURG., vol. 30, no. 3, 2004, pages 689 - 695
ISELI HANS PETER; KöRBER NICOLE; KOCH CHRISTIAN; KARL ANETT; PENK ANJA; HUSTER DANIEL; REICHENBACH ANDREAS; WIEDEMANN PETER; : "Scleral cross-linking by riboflavin and blue light application in young rabbits: damage threshold and eye growth inhibition", GRAEFE'S ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, SPRINGER BERLIN HEIDELBERG, BERLIN/HEIDELBERG, vol. 254, no. 1, 23 November 2015 (2015-11-23), Berlin/Heidelberg, pages 109 - 122, XP035880082, ISSN: 0721-832X, DOI: 10.1007/s00417-015-3213-x
J CATARACT REFRACT SURG, vol. 30, 2004, pages 689 - 695
ACTA OPHTHALMOL, vol. 87, 2009, pages 193 - 198
J CATARACT REFRACT SURG, vol. 39, 2013, pages 1184 - 1189
J CATARACT REFACT SURG., vol. 30, no. 3, 2004, pages 689 - 695
Attorney, Agent or Firm:
YAMAO, Norihito et al. (JP)
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