Title:
PREVENTION OR TREATMENT OF MYOPATHY USING MIR-33B INHIBITOR
Document Type and Number:
WIPO Patent Application WO/2022/230987
Kind Code:
A1
Abstract:
A prophylactic or therapeutic agent for myopathy, containing a miR-33b inhibitor, preferably an antisense oligonucleotide against miR-33b, as an active ingredient.
Inventors:
KOTERA JUN (JP)
ONO KOH (JP)
HORIE TAKAHIRO (JP)
SOWA NAOYA (JP)
IDE YUYA (JP)
OBIKA SATOSHI (JP)
KASAHARA YUYA (JP)
ONO KOH (JP)
HORIE TAKAHIRO (JP)
SOWA NAOYA (JP)
IDE YUYA (JP)
OBIKA SATOSHI (JP)
KASAHARA YUYA (JP)
Application Number:
PCT/JP2022/019329
Publication Date:
November 03, 2022
Filing Date:
April 28, 2022
Export Citation:
Assignee:
MITSUBISHI TANABE PHARMA CORP (JP)
UNIV KYOTO (JP)
UNIV OSAKA (JP)
NAT INST BIOMEDICAL INNOVATION HEALTH & NUTRITION (JP)
UNIV KYOTO (JP)
UNIV OSAKA (JP)
NAT INST BIOMEDICAL INNOVATION HEALTH & NUTRITION (JP)
International Classes:
A61K45/00; A61K31/7088; A61K31/7105; A61K31/712; A61K48/00; A61P21/00; A61P21/04; A61P43/00; C12N15/113
Domestic Patent References:
| WO2020160121A1 | 2020-08-06 | |||
| WO2021058524A1 | 2021-04-01 | |||
| WO2004076622A2 | 2004-09-10 | |||
| WO2012119051A2 | 2012-09-07 | |||
| WO2009006478A2 | 2009-01-08 | |||
| WO2008150729A2 | 2008-12-11 | |||
| WO2008154401A2 | 2008-12-18 | |||
| WO2011052436A1 | 2011-05-05 |
Foreign References:
| CN110665010A | 2020-01-10 | |||
| US7399845B2 | 2008-07-15 | |||
| US20040171570A1 | 2004-09-02 | |||
| US7427672B2 | 2008-09-23 |
Other References:
TANIGUCHI MASAAKI; NAKAJIMA IKUYO; CHIKUNI KOICHI; KOJIMA MISAKI; AWATA TAKASHI; MIKAWA SATOSHI: "MicroRNA-33b downregulates the differentiation and development of porcine preadipocytes", MOLECULAR BIOLOGY REPORTS, SPRINGER NETHERLANDS, NL, vol. 41, no. 2, 8 January 2014 (2014-01-08), NL , pages 1081 - 1090, XP035975888, ISSN: 0301-4851, DOI: 10.1007/s11033-013-2954-z
CRIADO-MESAS LOURDES, BALLESTER MARIA, CRESPO-PIAZUELO DANIEL, PASSOLS MAGÍ, CASTELLÓ ANNA, SÁNCHEZ ARMAND, FOLCH JOSEP M.: "Expression analysis of porcine miR-33a/b in liver, adipose tissue and muscle and its potential role in fatty acid metabolism", PLOS ONE, vol. 16, no. 1, 26 January 2021 (2021-01-26), pages e0245858, XP055982517, DOI: 10.1371/journal.pone.0245858
LIN YANCHENG, LIU ALLAN YI, FAN CHUANNAN, ZHENG HONG, LI YUAN, ZHANG CHUANKAI, WU SHASHA, YU DONGHONG, HUANG ZHENGJIE, LIU FAN, LU: "MicroRNA-33b Inhibits Breast Cancer Metastasis by Targeting HMGA2, SALL4 and Twist1", SCIENTIFIC REPORTS, vol. 5, no. 1, 1 September 2015 (2015-09-01), XP055982515, DOI: 10.1038/srep09995
WU LEIMING, LI YAPENG, ZHANG DIANHONG, HUANG ZHEN, DU BINBIN, WANG ZHENG, YANG LULU, ZHANG YANZHOU: "Retraction: LncRNA NEXN-AS1 attenuates proliferation and migration of vascular smooth muscle cells through sponging miR-33a/b", RSC ADVANCES, vol. 12, no. 44, 4 October 2022 (2022-10-04), pages 28637 - 28637, XP055982514, DOI: 10.1039/D2RA90099H
HOMEPAGE OF THE JAPANESE SOCIETY OF NEUROPATHOLOGY
J AM HEART ASSOC, vol. 8, no. 13, 2019, pages e012609
CLINICAL SCIENCE, vol. 133, no. 4, 1979, pages 583 - 595
BIOSCIENCE REPORTS, vol. 40, no. 6, 26 June 2020 (2020-06-26), ISSN: 1573-4935
NAT REV NEUROL, vol. 15, no. 7, July 2019 (2019-07-01), pages 373 - 386
ACTA NEUROPATHOLOGICA, vol. 134, 2017, pages 869 - 888
ALTSCHUL ET AL., J. MOL. BIOL., vol. 215, 1990, pages 403 410
ZHANGMADDEN, GENOME RES, vol. 7, no. 649, 1997, pages 656
SMITHWATERMAN, ADV. APPL. MATH, vol. 2, 1981, pages 482 489
CHATTOPADHYAYA ET AL., J. ORG. CHEM., vol. 74, 2009, pages 118 - 134
PROC. NATL. ACAD. SCI. USA., vol. 113, no. 21, 2016, pages 5898 - 903
MOL. PHARM., vol. 16, no. 2, 2019, pages 914 - 920
J. AM. CHEM. SOC., vol. 139, no. 9, 2017, pages 3446 - 3455
CRIADO-MESAS LOURDES, BALLESTER MARIA, CRESPO-PIAZUELO DANIEL, PASSOLS MAGÍ, CASTELLÓ ANNA, SÁNCHEZ ARMAND, FOLCH JOSEP M.: "Expression analysis of porcine miR-33a/b in liver, adipose tissue and muscle and its potential role in fatty acid metabolism", PLOS ONE, vol. 16, no. 1, 26 January 2021 (2021-01-26), pages e0245858, XP055982517, DOI: 10.1371/journal.pone.0245858
LIN YANCHENG, LIU ALLAN YI, FAN CHUANNAN, ZHENG HONG, LI YUAN, ZHANG CHUANKAI, WU SHASHA, YU DONGHONG, HUANG ZHENGJIE, LIU FAN, LU: "MicroRNA-33b Inhibits Breast Cancer Metastasis by Targeting HMGA2, SALL4 and Twist1", SCIENTIFIC REPORTS, vol. 5, no. 1, 1 September 2015 (2015-09-01), XP055982515, DOI: 10.1038/srep09995
WU LEIMING, LI YAPENG, ZHANG DIANHONG, HUANG ZHEN, DU BINBIN, WANG ZHENG, YANG LULU, ZHANG YANZHOU: "Retraction: LncRNA NEXN-AS1 attenuates proliferation and migration of vascular smooth muscle cells through sponging miR-33a/b", RSC ADVANCES, vol. 12, no. 44, 4 October 2022 (2022-10-04), pages 28637 - 28637, XP055982514, DOI: 10.1039/D2RA90099H
HOMEPAGE OF THE JAPANESE SOCIETY OF NEUROPATHOLOGY
J AM HEART ASSOC, vol. 8, no. 13, 2019, pages e012609
CLINICAL SCIENCE, vol. 133, no. 4, 1979, pages 583 - 595
BIOSCIENCE REPORTS, vol. 40, no. 6, 26 June 2020 (2020-06-26), ISSN: 1573-4935
NAT REV NEUROL, vol. 15, no. 7, July 2019 (2019-07-01), pages 373 - 386
ACTA NEUROPATHOLOGICA, vol. 134, 2017, pages 869 - 888
ALTSCHUL ET AL., J. MOL. BIOL., vol. 215, 1990, pages 403 410
ZHANGMADDEN, GENOME RES, vol. 7, no. 649, 1997, pages 656
SMITHWATERMAN, ADV. APPL. MATH, vol. 2, 1981, pages 482 489
CHATTOPADHYAYA ET AL., J. ORG. CHEM., vol. 74, 2009, pages 118 - 134
PROC. NATL. ACAD. SCI. USA., vol. 113, no. 21, 2016, pages 5898 - 903
MOL. PHARM., vol. 16, no. 2, 2019, pages 914 - 920
J. AM. CHEM. SOC., vol. 139, no. 9, 2017, pages 3446 - 3455
Attorney, Agent or Firm:
IP FIRM SHUWA (JP)
Download PDF:
Previous Patent: HAIR COSMETIC
Next Patent: AMMONIA-MIXED FUEL, PRODUCTION DEVICE FOR AMMONIA-MIXED FUEL, PRODUCTION METHOD FOR AMMONIA-MIXED FU...
Next Patent: AMMONIA-MIXED FUEL, PRODUCTION DEVICE FOR AMMONIA-MIXED FUEL, PRODUCTION METHOD FOR AMMONIA-MIXED FU...